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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FANCI
All Species:
26.36
Human Site:
S622
Identified Species:
44.62
UniProt:
Q9NVI1
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVI1
NP_001106849.1
1328
149324
S622
R
N
S
Q
L
A
N
S
V
M
Q
T
L
L
S
Chimpanzee
Pan troglodytes
XP_001166960
1328
149462
S622
R
N
S
Q
L
A
N
S
V
M
Q
T
L
L
S
Rhesus Macaque
Macaca mulatta
XP_001092590
1268
142835
L603
S
Q
Q
A
D
V
R
L
M
L
Y
E
G
F
Y
Dog
Lupus familis
XP_545849
1234
138558
Q569
L
R
R
C
L
G
Q
Q
A
D
V
R
L
M
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8K368
1330
149307
S621
R
N
S
Q
L
A
S
S
I
M
Q
T
L
F
S
Rat
Rattus norvegicus
XP_001064803
1332
149518
S621
R
N
S
Q
L
A
S
S
I
M
Q
T
L
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513065
736
82976
D71
E
C
I
V
L
Q
G
D
L
V
L
L
Q
E
P
Chicken
Gallus gallus
NP_001108323
1338
149271
S624
R
N
S
Q
L
A
S
S
I
M
E
T
L
L
S
Frog
Xenopus laevis
NP_001164682
1337
149488
S623
R
N
S
Q
L
A
S
S
V
M
Q
T
L
L
S
Zebra Danio
Brachydanio rerio
XP_001921139
1367
152995
S622
R
N
S
Q
L
A
S
S
I
T
Q
T
L
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122372
706
81709
Q41
S
D
E
S
Q
L
K
Q
R
K
L
I
E
Y
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190805
989
110178
D324
T
S
S
Q
I
Q
V
D
I
H
G
G
S
N
Q
Poplar Tree
Populus trichocarpa
XP_002315511
1406
157649
P616
A
D
P
S
C
G
G
P
V
L
D
F
L
L
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001119400
1470
164337
H617
I
D
P
S
S
G
G
H
V
L
D
F
L
M
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
93
81.4
N.A.
80.8
81.3
N.A.
39.7
66.9
66.9
59.4
N.A.
N.A.
20.4
N.A.
33.3
Protein Similarity:
100
99.6
94.2
86.5
N.A.
89.6
89.8
N.A.
46.9
81.6
81.5
75.9
N.A.
N.A.
33
N.A.
49.4
P-Site Identity:
100
100
0
13.3
N.A.
80
80
N.A.
6.6
80
93.3
80
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
100
13.3
20
N.A.
93.3
93.3
N.A.
20
100
100
93.3
N.A.
N.A.
6.6
N.A.
33.3
Percent
Protein Identity:
22.7
N.A.
N.A.
23.4
N.A.
N.A.
Protein Similarity:
44.1
N.A.
N.A.
43
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
50
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
8
0
8
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
22
0
0
8
0
0
15
0
8
15
0
0
0
0
% D
% Glu:
8
0
8
0
0
0
0
0
0
0
8
8
8
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
15
0
22
0
% F
% Gly:
0
0
0
0
0
22
22
0
0
0
8
8
8
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% H
% Ile:
8
0
8
0
8
0
0
0
36
0
0
8
0
0
8
% I
% Lys:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% K
% Leu:
8
0
0
0
65
8
0
8
8
22
15
8
72
43
8
% L
% Met:
0
0
0
0
0
0
0
0
8
43
0
0
0
15
0
% M
% Asn:
0
50
0
0
0
0
15
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
15
0
0
0
0
8
0
0
0
0
0
0
22
% P
% Gln:
0
8
8
58
8
15
8
15
0
0
43
0
8
0
8
% Q
% Arg:
50
8
8
0
0
0
8
0
8
0
0
8
0
0
0
% R
% Ser:
15
8
58
22
8
0
36
50
0
0
0
0
8
0
50
% S
% Thr:
8
0
0
0
0
0
0
0
0
8
0
50
0
0
0
% T
% Val:
0
0
0
8
0
8
8
0
36
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _