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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FANCI
All Species:
18.18
Human Site:
S222
Identified Species:
30.77
UniProt:
Q9NVI1
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVI1
NP_001106849.1
1328
149324
S222
Y
Q
L
L
V
L
S
S
K
G
S
R
K
S
V
Chimpanzee
Pan troglodytes
XP_001166960
1328
149462
S222
Y
Q
L
L
V
L
S
S
K
G
S
R
K
S
V
Rhesus Macaque
Macaca mulatta
XP_001092590
1268
142835
S222
Y
Q
L
L
V
L
S
S
K
G
S
R
K
S
V
Dog
Lupus familis
XP_545849
1234
138558
L191
P
P
L
V
Y
Q
L
L
V
L
S
S
K
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K368
1330
149307
S222
Y
Q
L
L
V
L
S
S
K
G
S
R
R
S
V
Rat
Rattus norvegicus
XP_001064803
1332
149518
S222
Y
Q
L
L
V
L
S
S
K
G
S
R
R
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513065
736
82976
Chicken
Gallus gallus
NP_001108323
1338
149271
A222
Y
Q
L
L
L
L
S
A
K
G
S
K
K
T
V
Frog
Xenopus laevis
NP_001164682
1337
149488
A221
Y
Q
L
L
L
L
S
A
K
G
S
K
K
N
I
Zebra Danio
Brachydanio rerio
XP_001921139
1367
152995
A224
Y
Q
L
L
L
L
S
A
K
G
C
K
K
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122372
706
81709
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190805
989
110178
Poplar Tree
Populus trichocarpa
XP_002315511
1406
157649
F215
R
E
F
L
E
K
V
F
K
G
M
R
R
V
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001119400
1470
164337
V219
E
L
V
E
K
V
F
V
G
I
K
L
I
D
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
93
81.4
N.A.
80.8
81.3
N.A.
39.7
66.9
66.9
59.4
N.A.
N.A.
20.4
N.A.
33.3
Protein Similarity:
100
99.6
94.2
86.5
N.A.
89.6
89.8
N.A.
46.9
81.6
81.5
75.9
N.A.
N.A.
33
N.A.
49.4
P-Site Identity:
100
100
100
20
N.A.
93.3
93.3
N.A.
0
73.3
66.6
66.6
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
100
26.6
N.A.
100
100
N.A.
0
100
100
86.6
N.A.
N.A.
0
N.A.
0
Percent
Protein Identity:
22.7
N.A.
N.A.
23.4
N.A.
N.A.
Protein Similarity:
44.1
N.A.
N.A.
43
N.A.
N.A.
P-Site Identity:
26.6
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
40
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
22
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% D
% Glu:
8
8
0
8
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
8
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
65
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
8
% I
% Lys:
0
0
0
0
8
8
0
0
65
0
8
22
50
0
0
% K
% Leu:
0
8
65
65
22
58
8
8
0
8
0
8
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
58
0
0
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
43
22
0
0
% R
% Ser:
0
0
0
0
0
0
58
36
0
0
58
8
0
36
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% T
% Val:
0
0
8
8
36
8
8
8
8
0
0
0
0
8
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
58
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _