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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FANCI
All Species:
14.85
Human Site:
S1018
Identified Species:
25.13
UniProt:
Q9NVI1
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVI1
NP_001106849.1
1328
149324
S1018
S
K
I
C
K
E
N
S
R
E
D
A
L
F
C
Chimpanzee
Pan troglodytes
XP_001166960
1328
149462
S1018
S
K
I
C
K
E
N
S
R
E
D
A
L
F
C
Rhesus Macaque
Macaca mulatta
XP_001092590
1268
142835
V983
H
V
L
Y
K
S
P
V
I
L
L
R
D
L
S
Dog
Lupus familis
XP_545849
1234
138558
L949
Y
K
S
P
V
T
L
L
R
D
L
S
Q
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8K368
1330
149307
S1014
S
K
I
C
K
E
Y
S
Q
E
D
A
S
F
C
Rat
Rattus norvegicus
XP_001064803
1332
149518
S1016
S
K
I
C
K
E
H
S
Q
E
D
A
S
F
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513065
736
82976
S451
N
L
H
V
R
C
R
S
P
V
S
L
L
R
D
Chicken
Gallus gallus
NP_001108323
1338
149271
D1020
C
K
E
N
A
L
E
D
L
S
C
C
K
G
L
Frog
Xenopus laevis
NP_001164682
1337
149488
N1020
V
K
I
C
K
E
T
N
I
E
D
V
Q
F
C
Zebra Danio
Brachydanio rerio
XP_001921139
1367
152995
I1019
K
E
T
N
F
E
D
I
A
L
T
K
G
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122372
706
81709
Y421
H
Y
T
D
C
L
K
Y
M
C
R
E
L
S
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190805
989
110178
T704
L
H
C
V
D
P
L
T
D
G
D
G
G
D
E
Poplar Tree
Populus trichocarpa
XP_002315511
1406
157649
L1042
L
L
V
I
G
E
K
L
P
R
K
Q
R
N
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001119400
1470
164337
A1020
P
M
I
T
D
F
I
A
Q
N
S
N
D
V
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
93
81.4
N.A.
80.8
81.3
N.A.
39.7
66.9
66.9
59.4
N.A.
N.A.
20.4
N.A.
33.3
Protein Similarity:
100
99.6
94.2
86.5
N.A.
89.6
89.8
N.A.
46.9
81.6
81.5
75.9
N.A.
N.A.
33
N.A.
49.4
P-Site Identity:
100
100
6.6
13.3
N.A.
80
80
N.A.
13.3
6.6
60
6.6
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
13.3
26.6
N.A.
86.6
93.3
N.A.
26.6
6.6
66.6
20
N.A.
N.A.
6.6
N.A.
13.3
Percent
Protein Identity:
22.7
N.A.
N.A.
23.4
N.A.
N.A.
Protein Similarity:
44.1
N.A.
N.A.
43
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
8
8
0
0
29
0
0
0
% A
% Cys:
8
0
8
36
8
8
0
0
0
8
8
8
0
0
36
% C
% Asp:
0
0
0
8
15
0
8
8
8
8
43
0
15
15
8
% D
% Glu:
0
8
8
0
0
50
8
0
0
36
0
8
0
0
15
% E
% Phe:
0
0
0
0
8
8
0
0
0
0
0
0
0
36
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
8
0
8
15
8
0
% G
% His:
15
8
8
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
43
8
0
0
8
8
15
0
0
0
0
0
8
% I
% Lys:
8
50
0
0
43
0
15
0
0
0
8
8
8
0
0
% K
% Leu:
15
15
8
0
0
15
15
15
8
15
15
8
29
15
15
% L
% Met:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
8
% M
% Asn:
8
0
0
15
0
0
15
8
0
8
0
8
0
8
0
% N
% Pro:
8
0
0
8
0
8
8
0
15
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
22
0
0
8
15
0
0
% Q
% Arg:
0
0
0
0
8
0
8
0
22
8
8
8
8
8
0
% R
% Ser:
29
0
8
0
0
8
0
36
0
8
15
8
15
8
15
% S
% Thr:
0
0
15
8
0
8
8
8
0
0
8
0
0
0
0
% T
% Val:
8
8
8
15
8
0
0
8
0
8
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
8
0
0
8
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _