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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMLHE
All Species:
28.18
Human Site:
Y128
Identified Species:
51.67
UniProt:
Q9NVH6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVH6
NP_060666.1
421
49518
Y128
P
D
G
H
V
T
K
Y
D
L
N
W
L
V
K
Chimpanzee
Pan troglodytes
XP_521349
253
29792
Rhesus Macaque
Macaca mulatta
XP_001099674
421
49482
Y128
P
D
G
H
V
T
K
Y
D
L
N
W
L
V
K
Dog
Lupus familis
XP_853649
421
49711
Y128
P
D
G
H
V
T
K
Y
D
L
D
W
L
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZE0
421
49591
Y128
P
D
G
H
V
T
R
Y
D
L
D
W
L
V
K
Rat
Rattus norvegicus
Q91ZW6
421
49549
Y128
P
D
G
H
V
T
R
Y
D
L
D
W
L
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514717
421
49328
Y128
P
D
G
H
V
T
R
Y
N
L
E
W
L
V
K
Chicken
Gallus gallus
Q5F4B3
418
48638
Q128
H
V
T
R
Y
G
L
Q
W
L
V
K
N
S
Y
Frog
Xenopus laevis
NP_001128540
421
49358
Y128
P
D
G
H
M
T
R
Y
G
L
E
W
L
V
Q
Zebra Danio
Brachydanio rerio
XP_682831
416
48101
L128
T
R
Y
N
L
A
W
L
A
Q
N
S
Y
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650886
364
42136
Q105
W
N
R
S
I
I
L
Q
N
E
R
H
L
R
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19000
421
48418
I136
Q
T
W
G
K
A
E
I
E
G
K
L
K
K
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q96UB1
471
52612
Y138
S
D
N
H
T
S
T
Y
P
W
P
F
L
S
F
Conservation
Percent
Protein Identity:
100
59.8
98.5
94
N.A.
88.1
86.4
N.A.
85.9
81.7
69.5
67.9
N.A.
29.4
N.A.
24.4
N.A.
Protein Similarity:
100
60
98.8
96.6
N.A.
93.1
92.8
N.A.
90.5
90.2
82.6
79.8
N.A.
47.7
N.A.
42.7
N.A.
P-Site Identity:
100
0
100
86.6
N.A.
86.6
86.6
N.A.
80
6.6
66.6
6.6
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
0
100
100
N.A.
100
100
N.A.
93.3
6.6
86.6
20
N.A.
26.6
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
31
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
45.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
16
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
62
0
0
0
0
0
0
39
0
24
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
8
8
16
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
24
% F
% Gly:
0
0
54
8
0
8
0
0
8
8
0
0
0
0
8
% G
% His:
8
0
0
62
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
8
8
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
24
0
0
0
8
8
8
8
39
% K
% Leu:
0
0
0
0
8
0
16
8
0
62
0
8
70
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
8
0
0
0
0
16
0
24
0
8
0
0
% N
% Pro:
54
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
16
0
8
0
0
0
0
8
% Q
% Arg:
0
8
8
8
0
0
31
0
0
0
8
0
0
8
8
% R
% Ser:
8
0
0
8
0
8
0
0
0
0
0
8
0
16
0
% S
% Thr:
8
8
8
0
8
54
8
0
0
0
0
0
0
0
0
% T
% Val:
0
8
0
0
47
0
0
0
0
0
8
0
0
54
0
% V
% Trp:
8
0
8
0
0
0
8
0
8
8
0
54
0
0
0
% W
% Tyr:
0
0
8
0
8
0
0
62
0
0
0
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _