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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ETNK2
All Species:
19.39
Human Site:
S241
Identified Species:
42.67
UniProt:
Q9NVF9
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVF9
NP_060678
386
44781
S241
E
H
L
S
Q
L
E
S
P
V
V
F
C
H
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001098880
386
44714
S241
E
H
L
S
Q
L
E
S
P
V
V
F
C
H
N
Dog
Lupus familis
XP_536094
341
40057
C205
F
C
H
N
D
L
L
C
K
N
I
I
Y
D
S
Cat
Felis silvestris
Mouse
Mus musculus
A7MCT6
385
44549
S240
E
H
L
S
Q
L
D
S
P
V
V
F
C
H
N
Rat
Rattus norvegicus
O54783
394
45082
S234
T
L
L
D
A
T
P
S
P
V
V
F
C
H
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515595
310
36271
N174
L
C
K
N
I
I
Y
N
E
T
E
G
H
V
R
Chicken
Gallus gallus
XP_424313
367
41475
A224
E
M
L
E
H
E
L
A
W
M
K
D
T
L
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001029347
360
41979
S210
E
H
L
S
Q
L
G
S
P
V
V
L
C
H
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54352
518
59544
S369
E
Y
L
E
A
L
D
S
P
I
V
F
S
H
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784116
355
41113
A205
S
V
L
T
S
L
D
A
P
V
V
F
S
H
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P20485
582
66298
K322
Q
G
I
E
Q
V
N
K
N
L
I
F
C
H
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.8
74.8
N.A.
87.3
27.9
N.A.
57.7
54.1
N.A.
59.3
N.A.
34.9
N.A.
N.A.
41.9
Protein Similarity:
100
N.A.
98.1
79.2
N.A.
91.9
47.2
N.A.
65
67
N.A.
72.5
N.A.
47.6
N.A.
N.A.
61.1
P-Site Identity:
100
N.A.
100
6.6
N.A.
93.3
60
N.A.
0
13.3
N.A.
86.6
N.A.
60
N.A.
N.A.
53.3
P-Site Similarity:
100
N.A.
100
26.6
N.A.
100
60
N.A.
20
33.3
N.A.
86.6
N.A.
80
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
19
0
0
19
0
0
0
0
0
0
0
% A
% Cys:
0
19
0
0
0
0
0
10
0
0
0
0
55
0
0
% C
% Asp:
0
0
0
10
10
0
28
0
0
0
0
10
0
10
0
% D
% Glu:
55
0
0
28
0
10
19
0
10
0
10
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
64
0
0
0
% F
% Gly:
0
10
0
0
0
0
10
0
0
0
0
10
0
0
0
% G
% His:
0
37
10
0
10
0
0
0
0
0
0
0
10
73
0
% H
% Ile:
0
0
10
0
10
10
0
0
0
10
19
10
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
10
10
0
10
0
0
0
0
% K
% Leu:
10
10
73
0
0
64
19
0
0
10
0
10
0
10
0
% L
% Met:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
19
0
0
10
10
10
10
0
0
0
0
73
% N
% Pro:
0
0
0
0
0
0
10
0
64
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
46
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
10
0
0
37
10
0
0
55
0
0
0
0
19
0
19
% S
% Thr:
10
0
0
10
0
10
0
0
0
10
0
0
10
0
0
% T
% Val:
0
10
0
0
0
10
0
0
0
55
64
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
10
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _