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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD4
All Species:
34.55
Human Site:
Y129
Identified Species:
63.33
UniProt:
Q9NVD3
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVD3
NP_001007260.1
440
50416
Y129
H
R
S
L
W
K
P
Y
L
E
I
L
P
K
A
Chimpanzee
Pan troglodytes
XP_001168912
440
50497
Y129
H
R
S
L
W
K
P
Y
L
E
I
L
P
K
A
Rhesus Macaque
Macaca mulatta
XP_001085715
440
50622
Y129
D
R
S
L
W
K
P
Y
L
E
I
L
P
K
A
Dog
Lupus familis
XP_544872
476
54805
Y165
D
Q
S
L
W
K
P
Y
L
E
I
L
P
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
P58467
439
49818
Y128
C
R
S
L
W
K
S
Y
L
D
I
L
P
K
S
Rat
Rattus norvegicus
NP_001107219
439
49656
Y128
S
H
S
L
W
K
S
Y
L
D
I
L
P
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512617
707
77741
Y129
A
R
S
L
W
Q
P
Y
L
G
V
L
P
Q
A
Chicken
Gallus gallus
NP_001025965
439
50536
Y128
E
R
S
L
W
K
P
Y
L
D
V
L
P
K
T
Frog
Xenopus laevis
NP_001079674
456
52090
Y129
D
C
S
Q
W
K
P
Y
L
D
V
I
P
S
T
Zebra Danio
Brachydanio rerio
NP_001039027
440
51126
Y130
E
A
S
E
W
N
P
Y
I
D
I
L
P
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_490849
401
46372
A95
F
E
D
T
E
H
S
A
W
S
P
Y
L
K
V
Sea Urchin
Strong. purpuratus
XP_001201449
320
36303
R14
K
K
G
L
S
R
Q
R
Q
K
P
T
P
Y
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03942
479
55931
D171
I
P
A
I
W
N
C
D
P
N
S
R
Y
H
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.7
77
N.A.
77
75.4
N.A.
42.2
63.4
52.8
48.1
N.A.
N.A.
N.A.
24.7
23.8
Protein Similarity:
100
99.7
98.6
84.2
N.A.
86.8
85.9
N.A.
50.6
78.4
70.6
65.2
N.A.
N.A.
N.A.
44.3
39.5
P-Site Identity:
100
100
93.3
80
N.A.
73.3
66.6
N.A.
66.6
73.3
46.6
53.3
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
100
100
93.3
93.3
N.A.
86.6
80
N.A.
86.6
86.6
66.6
66.6
N.A.
N.A.
N.A.
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
0
0
0
8
0
0
0
0
0
0
39
% A
% Cys:
8
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
24
0
8
0
0
0
0
8
0
39
0
0
0
0
0
% D
% Glu:
16
8
0
8
8
0
0
0
0
31
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% G
% His:
16
8
0
0
0
8
0
0
0
0
0
0
0
8
0
% H
% Ile:
8
0
0
8
0
0
0
0
8
0
54
8
0
0
0
% I
% Lys:
8
8
0
0
0
62
0
0
0
8
0
0
0
62
0
% K
% Leu:
0
0
0
70
0
0
0
0
70
0
0
70
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
16
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
62
0
8
0
16
0
85
0
0
% P
% Gln:
0
8
0
8
0
8
8
0
8
0
0
0
0
16
8
% Q
% Arg:
0
47
0
0
0
8
0
8
0
0
0
8
0
0
0
% R
% Ser:
8
0
77
0
8
0
24
0
0
8
8
0
0
8
24
% S
% Thr:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
24
% T
% Val:
0
0
0
0
0
0
0
0
0
0
24
0
0
0
8
% V
% Trp:
0
0
0
0
85
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
77
0
0
0
8
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _