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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD4
All Species:
30
Human Site:
S67
Identified Species:
55
UniProt:
Q9NVD3
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVD3
NP_001007260.1
440
50416
S67
R
G
L
M
S
Q
T
S
L
Q
E
G
Q
M
I
Chimpanzee
Pan troglodytes
XP_001168912
440
50497
S67
R
G
L
M
S
Q
T
S
L
Q
E
G
Q
M
I
Rhesus Macaque
Macaca mulatta
XP_001085715
440
50622
S67
R
G
L
M
S
Q
T
S
L
Q
E
G
Q
M
I
Dog
Lupus familis
XP_544872
476
54805
S103
R
G
L
M
S
K
T
S
L
R
E
G
Q
M
I
Cat
Felis silvestris
Mouse
Mus musculus
P58467
439
49818
S66
R
G
L
M
S
K
A
S
L
Q
E
G
Q
V
M
Rat
Rattus norvegicus
NP_001107219
439
49656
S66
R
G
L
M
S
K
A
S
L
Q
E
G
Q
V
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512617
707
77741
S67
R
G
L
M
A
T
K
S
L
K
A
G
E
M
I
Chicken
Gallus gallus
NP_001025965
439
50536
A66
R
G
L
M
T
T
K
A
L
Q
A
G
E
L
V
Frog
Xenopus laevis
NP_001079674
456
52090
D67
R
G
L
M
A
T
R
D
L
K
P
G
E
L
I
Zebra Danio
Brachydanio rerio
NP_001039027
440
51126
T68
R
G
L
M
A
T
Q
T
I
K
A
K
N
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_490849
401
46372
Y33
G
N
C
G
N
G
I
Y
A
T
T
G
F
R
T
Sea Urchin
Strong. purpuratus
XP_001201449
320
36303
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03942
479
55931
S109
D
P
R
Y
G
L
Y
S
E
L
S
K
E
F
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.7
77
N.A.
77
75.4
N.A.
42.2
63.4
52.8
48.1
N.A.
N.A.
N.A.
24.7
23.8
Protein Similarity:
100
99.7
98.6
84.2
N.A.
86.8
85.9
N.A.
50.6
78.4
70.6
65.2
N.A.
N.A.
N.A.
44.3
39.5
P-Site Identity:
100
100
100
86.6
N.A.
73.3
80
N.A.
60
46.6
46.6
26.6
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
80
80
73.3
60
N.A.
N.A.
N.A.
13.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
24
0
16
8
8
0
24
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
8
0
47
0
31
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% F
% Gly:
8
77
0
8
8
8
0
0
0
0
0
77
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
54
% I
% Lys:
0
0
0
0
0
24
16
0
0
24
0
16
0
0
0
% K
% Leu:
0
0
77
0
0
8
0
0
70
8
0
0
0
16
8
% L
% Met:
0
0
0
77
0
0
0
0
0
0
0
0
0
39
8
% M
% Asn:
0
8
0
0
8
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
24
8
0
0
47
0
0
47
0
0
% Q
% Arg:
77
0
8
0
0
0
8
0
0
8
0
0
0
8
0
% R
% Ser:
0
0
0
0
47
0
0
62
0
0
8
0
0
8
0
% S
% Thr:
0
0
0
0
8
31
31
8
0
8
8
0
0
0
8
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
8
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _