KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD4
All Species:
21.52
Human Site:
S28
Identified Species:
39.44
UniProt:
Q9NVD3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVD3
NP_001007260.1
440
50416
S28
E
S
R
G
V
N
E
S
H
K
S
E
F
I
E
Chimpanzee
Pan troglodytes
XP_001168912
440
50497
S28
E
S
R
G
V
N
E
S
H
K
S
E
F
I
E
Rhesus Macaque
Macaca mulatta
XP_001085715
440
50622
S28
E
P
R
G
V
N
E
S
H
K
S
E
F
I
E
Dog
Lupus familis
XP_544872
476
54805
S64
S
S
G
T
V
N
E
S
Y
K
P
E
F
I
E
Cat
Felis silvestris
Mouse
Mus musculus
P58467
439
49818
Y28
S
R
A
V
N
E
S
Y
R
S
E
F
I
E
L
Rat
Rattus norvegicus
NP_001107219
439
49656
R28
R
G
V
N
E
S
C
R
S
E
F
I
E
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512617
707
77741
S28
E
P
N
G
V
N
E
S
H
Q
P
E
F
I
E
Chicken
Gallus gallus
NP_001025965
439
50536
H28
M
Y
G
V
N
C
S
H
K
L
E
Y
I
K
L
Frog
Xenopus laevis
NP_001079674
456
52090
S28
K
S
Y
A
A
N
R
S
H
E
W
Q
Y
I
Q
Zebra Danio
Brachydanio rerio
NP_001039027
440
51126
S29
D
F
S
I
V
T
L
S
H
E
A
Q
F
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_490849
401
46372
Sea Urchin
Strong. purpuratus
XP_001201449
320
36303
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03942
479
55931
F70
I
L
Y
H
I
S
K
F
N
K
E
L
N
I
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.7
77
N.A.
77
75.4
N.A.
42.2
63.4
52.8
48.1
N.A.
N.A.
N.A.
24.7
23.8
Protein Similarity:
100
99.7
98.6
84.2
N.A.
86.8
85.9
N.A.
50.6
78.4
70.6
65.2
N.A.
N.A.
N.A.
44.3
39.5
P-Site Identity:
100
100
93.3
66.6
N.A.
0
0
N.A.
73.3
0
33.3
26.6
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
100
93.3
73.3
N.A.
0
20
N.A.
80
0
66.6
60
N.A.
N.A.
N.A.
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
0
0
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
31
0
0
0
8
8
39
0
0
24
24
39
8
8
39
% E
% Phe:
0
8
0
0
0
0
0
8
0
0
8
8
47
0
0
% F
% Gly:
0
8
16
31
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
8
47
0
0
0
0
0
0
% H
% Ile:
8
0
0
8
8
0
0
0
0
0
0
8
16
54
0
% I
% Lys:
8
0
0
0
0
0
8
0
8
39
0
0
0
8
0
% K
% Leu:
0
8
0
0
0
0
8
0
0
8
0
8
0
8
24
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
16
47
0
0
8
0
0
0
8
0
0
% N
% Pro:
0
16
0
0
0
0
0
0
0
0
16
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
16
0
0
8
% Q
% Arg:
8
8
24
0
0
0
8
8
8
0
0
0
0
0
8
% R
% Ser:
16
31
8
0
0
16
16
54
8
8
24
0
0
0
0
% S
% Thr:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
8
16
47
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
8
16
0
0
0
0
8
8
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _