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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UQCC All Species: 26.36
Human Site: S261 Identified Species: 52.73
UniProt: Q9NVA1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVA1 NP_060714.3 299 34572 S261 K Q I Q Y L D S M N G E D L L
Chimpanzee Pan troglodytes XP_514604 299 34483 S261 K Q I Q Y L D S M N G E D L L
Rhesus Macaque Macaca mulatta XP_001099909 298 34239 S260 K Q M Q Y L D S M N G E D L L
Dog Lupus familis XP_851851 299 34633 S261 K Q M Q Y L D S M N G E D L L
Cat Felis silvestris
Mouse Mus musculus Q9CWU6 295 34281 S257 K Q M Q Y L D S M N G E D L L
Rat Rattus norvegicus NP_001102916 299 34528 S261 K Q M Q Y L D S M N G E D L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006285 302 34325 A264 K Q V Q H L D A L S G E D L L
Frog Xenopus laevis Q9W6I0 200 23354 L163 Q V Q F L D T L D G E D L L L
Zebra Danio Brachydanio rerio NP_001070223 286 32798 A248 K Q M Q F I D A L D G E D L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648064 259 29416 E222 C D D Y A Q I E R L V K Y V R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001175737 343 38828 S294 Q Q V Q Y L D S L D S S K L L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P21560 335 39065 F286 R E F A T G K F K F V P P G V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 95.9 90.3 N.A. 86.9 86.2 N.A. N.A. 66.8 50.1 55.8 N.A. 30.4 N.A. N.A. 35.5
Protein Similarity: 100 99.6 96.6 93.9 N.A. 91.3 91.3 N.A. N.A. 77.1 58.1 73.2 N.A. 48.8 N.A. N.A. 53.3
P-Site Identity: 100 100 93.3 93.3 N.A. 93.3 93.3 N.A. N.A. 66.6 13.3 60 N.A. 0 N.A. N.A. 53.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 26.6 100 N.A. 13.3 N.A. N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 9 0 0 17 0 0 0 0 0 0 0 % A
% Cys: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 9 0 0 9 75 0 9 17 0 9 67 0 0 % D
% Glu: 0 9 0 0 0 0 0 9 0 0 9 67 0 0 0 % E
% Phe: 0 0 9 9 9 0 0 9 0 9 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 9 0 0 0 9 67 0 0 9 0 % G
% His: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 17 0 0 9 9 0 0 0 0 0 0 0 0 % I
% Lys: 67 0 0 0 0 0 9 0 9 0 0 9 9 0 0 % K
% Leu: 0 0 0 0 9 67 0 9 25 9 0 0 9 84 84 % L
% Met: 0 0 42 0 0 0 0 0 50 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 50 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 9 9 0 0 % P
% Gln: 17 75 9 75 0 9 0 0 0 0 0 0 0 0 0 % Q
% Arg: 9 0 0 0 0 0 0 0 9 0 0 0 0 0 9 % R
% Ser: 0 0 0 0 0 0 0 59 0 9 9 9 0 0 0 % S
% Thr: 0 0 0 0 9 0 9 0 0 0 0 0 0 0 0 % T
% Val: 0 9 17 0 0 0 0 0 0 0 17 0 0 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 59 0 0 0 0 0 0 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _