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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACOXL All Species: 6.36
Human Site: S225 Identified Species: 14
UniProt: Q9NUZ1 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NUZ1 NP_001098986.1 547 61795 S225 H S P I R N K S A R F N A M L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_854528 587 65947 S202 H S P I K N K S A R F N A M L
Cat Felis silvestris
Mouse Mus musculus Q9DBS4 632 70688 N251 H S P I Q S K N A R F N A I L
Rat Rattus norvegicus Q63448 700 78427 R294 H T P F K D V R Q R L G A S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505614 428 47312 A129 V K G I Q T E A T F D L T T Q
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_697559 652 73140 G275 Y S S P A L R G N R F N A M L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KML2 669 74269 V279 V L P D G T Y V A P K N S V L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34355 659 74696 H268 R R N M L M K H S K V S K E G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002309985 689 77604 N323 T S S L P T I N K R F A A T L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O65201 692 77462 N326 T S S L P T I N K R F G A T L
Baker's Yeast Sacchar. cerevisiae P13711 748 84024 T318 R S P D G S V T V K T E P Q L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 78.1 N.A. 67.7 26.4 N.A. 44.4 N.A. N.A. 56.1 N.A. 25.2 N.A. 26.7 N.A.
Protein Similarity: 100 N.A. N.A. 82.4 N.A. 76.4 44.7 N.A. 55.7 N.A. N.A. 67.1 N.A. 42.5 N.A. 41.8 N.A.
P-Site Identity: 100 N.A. N.A. 93.3 N.A. 73.3 33.3 N.A. 6.6 N.A. N.A. 46.6 N.A. 26.6 N.A. 6.6 N.A.
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 53.3 N.A. 26.6 N.A. N.A. 60 N.A. 40 N.A. 33.3 N.A.
Percent
Protein Identity: 33 N.A. N.A. 33.8 23.9 N.A.
Protein Similarity: 49.4 N.A. N.A. 49.1 40.1 N.A.
P-Site Identity: 33.3 N.A. N.A. 33.3 20 N.A.
P-Site Similarity: 46.6 N.A. N.A. 46.6 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 10 37 0 0 10 64 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 19 0 10 0 0 0 0 10 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 10 0 0 0 0 10 0 10 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 10 55 0 0 0 0 % F
% Gly: 0 0 10 0 19 0 0 10 0 0 0 19 0 0 10 % G
% His: 37 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 37 0 0 19 0 0 0 0 0 0 10 0 % I
% Lys: 0 10 0 0 19 0 37 0 19 19 10 0 10 0 0 % K
% Leu: 0 10 0 19 10 10 0 0 0 0 10 10 0 0 82 % L
% Met: 0 0 0 10 0 10 0 0 0 0 0 0 0 28 0 % M
% Asn: 0 0 10 0 0 19 0 28 10 0 0 46 0 0 0 % N
% Pro: 0 0 55 10 19 0 0 0 0 10 0 0 10 0 0 % P
% Gln: 0 0 0 0 19 0 0 0 10 0 0 0 0 10 10 % Q
% Arg: 19 10 0 0 10 0 10 10 0 64 0 0 0 0 0 % R
% Ser: 0 64 28 0 0 19 0 19 10 0 0 10 10 10 0 % S
% Thr: 19 10 0 0 0 37 0 10 10 0 10 0 10 28 0 % T
% Val: 19 0 0 0 0 0 19 10 10 0 10 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _