KinATLAS
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DrugKiNET
KiNET-AM
Kinector
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGPAT5
All Species:
15.45
Human Site:
Y221
Identified Species:
28.33
UniProt:
Q9NUQ2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NUQ2
NP_060831.2
364
42072
Y221
A
F
D
C
M
K
N
Y
L
D
A
I
Y
D
V
Chimpanzee
Pan troglodytes
XP_519588
364
42095
Y221
A
F
D
C
M
K
N
Y
L
D
A
I
Y
D
V
Rhesus Macaque
Macaca mulatta
XP_001098129
364
42096
Y221
A
F
D
C
M
K
N
Y
L
D
A
I
Y
D
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
NP_081068
365
42184
H221
A
F
D
S
M
K
S
H
L
D
A
I
Y
D
V
Rat
Rattus norvegicus
NP_001128216
359
41513
H215
A
F
D
S
M
K
S
H
L
D
A
I
Y
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506591
349
38628
M220
S
E
R
G
R
T
F
M
N
V
I
H
V
N
M
Chicken
Gallus gallus
XP_419916
365
42358
Y221
A
I
D
T
M
K
D
Y
L
D
A
V
Y
D
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001070213
365
41805
H221
A
I
E
T
M
R
E
H
L
D
A
V
Y
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_491479
368
41786
T229
L
A
L
D
N
L
S
T
L
D
A
I
Y
D
V
Sea Urchin
Strong. purpuratus
XP_001182441
365
42047
F232
V
F
P
E
G
T
R
F
R
P
E
K
E
E
V
Poplar Tree
Populus trichocarpa
XP_002327077
372
42900
F250
Y
K
D
Q
L
P
T
F
L
D
N
V
F
G
T
Maize
Zea mays
NP_001151948
404
45744
F268
Y
K
H
R
P
P
T
F
L
D
N
V
Y
G
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565098
378
43045
L237
S
L
D
A
V
Y
D
L
T
I
A
Y
K
P
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.1
N.A.
N.A.
81.6
80.2
N.A.
46.1
77.2
N.A.
68.2
N.A.
N.A.
N.A.
35.8
21.9
Protein Similarity:
100
100
99.7
N.A.
N.A.
92.3
91.2
N.A.
57.9
89.8
N.A.
83.2
N.A.
N.A.
N.A.
56.5
39.4
P-Site Identity:
100
100
100
N.A.
N.A.
80
80
N.A.
0
73.3
N.A.
46.6
N.A.
N.A.
N.A.
46.6
13.3
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
93.3
N.A.
20
86.6
N.A.
80
N.A.
N.A.
N.A.
53.3
26.6
Percent
Protein Identity:
28.7
25
N.A.
26.9
N.A.
N.A.
Protein Similarity:
50.5
46.7
N.A.
47.6
N.A.
N.A.
P-Site Identity:
20
26.6
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
46.6
40
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
54
8
0
8
0
0
0
0
0
0
70
0
0
0
0
% A
% Cys:
0
0
0
24
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
62
8
0
0
16
0
0
77
0
0
0
62
0
% D
% Glu:
0
8
8
8
0
0
8
0
0
0
8
0
8
8
0
% E
% Phe:
0
47
0
0
0
0
8
24
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
8
8
0
0
0
0
0
0
0
0
16
0
% G
% His:
0
0
8
0
0
0
0
24
0
0
0
8
0
0
0
% H
% Ile:
0
16
0
0
0
0
0
0
0
8
8
47
0
0
8
% I
% Lys:
0
16
0
0
0
47
0
0
0
0
0
8
8
0
0
% K
% Leu:
8
8
8
0
8
8
0
8
77
0
0
0
0
0
0
% L
% Met:
0
0
0
0
54
0
0
8
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
8
0
24
0
8
0
16
0
0
8
0
% N
% Pro:
0
0
8
0
8
16
0
0
0
8
0
0
0
8
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
8
8
8
8
0
8
0
0
0
0
0
8
% R
% Ser:
16
0
0
16
0
0
24
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
16
0
16
16
8
8
0
0
0
0
0
8
% T
% Val:
8
0
0
0
8
0
0
0
0
8
0
31
8
0
70
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
0
0
0
0
8
0
31
0
0
0
8
70
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _