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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCXD1
All Species:
4.85
Human Site:
S281
Identified Species:
10.67
UniProt:
Q9NUJ7
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NUJ7
NP_060860.1
323
36668
S281
L
P
N
L
P
R
L
S
A
W
V
R
E
Q
C
Chimpanzee
Pan troglodytes
XP_001146704
329
37141
A281
L
V
H
R
N
L
P
A
I
L
D
W
V
K
T
Rhesus Macaque
Macaca mulatta
XP_001118970
151
17268
E114
I
L
A
C
R
N
F
E
G
L
S
E
D
L
H
Dog
Lupus familis
XP_850882
403
44382
R361
L
P
S
L
P
C
L
R
A
W
V
R
E
Q
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHS4
345
38699
T303
R
R
S
L
P
L
M
T
E
W
V
C
A
Q
Q
Rat
Rattus norvegicus
XP_001080726
362
40155
T320
R
R
S
V
P
L
T
T
Q
W
V
R
A
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505824
133
14947
L96
E
L
N
V
T
E
Q
L
D
C
G
I
R
Y
L
Chicken
Gallus gallus
NP_001122109
336
38712
K276
L
R
S
L
P
C
L
K
I
W
V
R
K
Q
Y
Frog
Xenopus laevis
NP_001079447
307
35506
I268
V
R
R
N
L
P
R
I
L
K
W
V
E
M
Q
Zebra Danio
Brachydanio rerio
Q567I4
309
35461
K268
R
S
Y
S
L
L
M
K
W
V
K
Q
Q
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791466
320
36304
Q281
F
A
L
T
A
I
M
Q
T
K
I
F
L
K
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34
45.5
66.5
N.A.
65.5
61.8
N.A.
27.2
57.7
35.2
42.7
N.A.
N.A.
N.A.
N.A.
31.8
Protein Similarity:
100
54.7
45.8
72.4
N.A.
76.5
72.9
N.A.
33.1
70.5
53.8
62.8
N.A.
N.A.
N.A.
N.A.
52.6
P-Site Identity:
100
6.6
0
80
N.A.
33.3
33.3
N.A.
6.6
53.3
6.6
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
26.6
13.3
86.6
N.A.
53.3
53.3
N.A.
13.3
66.6
13.3
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
10
0
0
10
19
0
0
0
19
0
0
% A
% Cys:
0
0
0
10
0
19
0
0
0
10
0
10
0
0
19
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
10
0
10
0
10
% D
% Glu:
10
0
0
0
0
10
0
10
10
0
0
10
28
0
0
% E
% Phe:
10
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
10
0
0
0
0
10
0
10
19
0
10
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
19
0
19
10
0
10
19
0
% K
% Leu:
37
19
10
37
19
37
28
10
10
19
0
0
10
10
10
% L
% Met:
0
0
0
0
0
0
28
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
19
10
10
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
19
0
0
46
10
10
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
10
10
10
0
0
10
10
46
28
% Q
% Arg:
28
37
10
10
10
10
10
10
0
0
0
37
10
10
0
% R
% Ser:
0
10
37
10
0
0
0
10
0
0
10
0
0
0
0
% S
% Thr:
0
0
0
10
10
0
10
19
10
0
0
0
0
0
10
% T
% Val:
10
10
0
19
0
0
0
0
0
10
46
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
46
10
10
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _