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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACSS1
All Species:
21.52
Human Site:
S415
Identified Species:
52.59
UniProt:
Q9NUB1
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NUB1
NP_115890.2
689
74857
S415
S
S
L
R
T
L
G
S
V
G
E
P
I
N
C
Chimpanzee
Pan troglodytes
XP_001149014
699
75890
S414
S
S
L
R
T
L
G
S
V
G
E
P
I
N
C
Rhesus Macaque
Macaca mulatta
XP_001099300
688
74713
S414
S
S
L
R
T
L
G
S
V
G
E
P
I
N
C
Dog
Lupus familis
XP_534200
628
68196
C377
K
V
V
G
D
G
R
C
T
L
V
D
T
W
W
Cat
Felis silvestris
Mouse
Mus musculus
Q99NB1
682
74605
S408
S
S
L
R
T
L
G
S
V
G
E
P
I
N
H
Rat
Rattus norvegicus
NP_001099994
682
74873
S408
S
S
L
R
T
L
G
S
V
G
E
P
I
N
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507198
478
52602
G230
A
D
I
G
W
I
T
G
H
T
Y
V
V
Y
G
Chicken
Gallus gallus
XP_415011
602
67099
V354
G
E
G
R
C
T
L
V
D
T
W
W
Q
T
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001074125
693
76670
S419
S
S
L
K
T
L
A
S
V
G
E
P
I
N
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790649
655
73166
C386
S
T
L
R
T
L
G
C
V
G
E
P
L
N
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
97.2
74.7
N.A.
86.9
85.9
N.A.
59
68.3
N.A.
68.6
N.A.
N.A.
N.A.
N.A.
56
Protein Similarity:
100
98
98.5
80.6
N.A.
92.5
92.1
N.A.
64.3
77.7
N.A.
80.5
N.A.
N.A.
N.A.
N.A.
69.3
P-Site Identity:
100
100
100
0
N.A.
93.3
93.3
N.A.
0
6.6
N.A.
80
N.A.
N.A.
N.A.
N.A.
73.3
P-Site Similarity:
100
100
100
6.6
N.A.
93.3
93.3
N.A.
26.6
6.6
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
20
0
0
0
0
0
0
30
% C
% Asp:
0
10
0
0
10
0
0
0
10
0
0
10
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
70
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
10
20
0
10
60
10
0
70
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
40
% H
% Ile:
0
0
10
0
0
10
0
0
0
0
0
0
60
0
0
% I
% Lys:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
70
0
0
70
10
0
0
10
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
70
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
70
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
70
0
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
70
60
0
0
0
0
0
60
0
0
0
0
0
0
0
% S
% Thr:
0
10
0
0
70
10
10
0
10
20
0
0
10
10
0
% T
% Val:
0
10
10
0
0
0
0
10
70
0
10
10
10
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
10
10
0
10
10
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _