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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP8A2
All Species:
25.15
Human Site:
T453
Identified Species:
46.11
UniProt:
Q9NTI2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NTI2
NP_057613.4
1148
129242
T453
N
I
E
D
R
H
P
T
A
P
C
I
Q
E
F
Chimpanzee
Pan troglodytes
XP_522636
1304
144347
T609
N
I
E
D
R
H
P
T
A
P
C
I
Q
E
F
Rhesus Macaque
Macaca mulatta
XP_001092901
1188
133474
T493
N
I
E
D
R
H
P
T
A
P
C
I
Q
E
F
Dog
Lupus familis
XP_543162
1175
133105
T474
N
F
E
N
G
H
P
T
K
D
Y
I
K
E
F
Cat
Felis silvestris
Mouse
Mus musculus
P98200
1148
129398
T453
N
I
E
D
Q
H
P
T
A
P
C
I
Q
E
F
Rat
Rattus norvegicus
XP_223390
1134
128100
S450
S
P
D
E
W
Q
S
S
Q
F
G
D
E
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518853
932
104820
A249
M
M
A
V
C
H
T
A
V
P
E
R
E
G
D
Chicken
Gallus gallus
XP_417130
1170
131762
T475
N
I
E
N
D
H
P
T
A
V
H
I
Q
E
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002666697
916
102033
I234
D
G
E
T
N
L
K
I
R
Q
G
L
S
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001137649
1324
149578
T632
N
I
L
G
R
H
E
T
S
A
V
I
E
E
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200260
1167
132097
I463
T
H
T
T
A
P
H
I
R
M
F
V
T
M
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XIE6
1213
137734
D488
W
R
N
E
P
N
P
D
L
C
K
E
L
F
R
Baker's Yeast
Sacchar. cerevisiae
P39524
1355
153826
F626
D
S
P
I
I
N
D
F
L
T
L
L
A
T
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88
95
67.2
N.A.
94.6
65.6
N.A.
54
82
N.A.
58.8
N.A.
49.2
N.A.
N.A.
56.7
Protein Similarity:
100
88
95.4
78.8
N.A.
97.2
79
N.A.
66.1
89.9
N.A.
65.7
N.A.
63.5
N.A.
N.A.
74.5
P-Site Identity:
100
100
100
53.3
N.A.
93.3
0
N.A.
13.3
73.3
N.A.
6.6
N.A.
53.3
N.A.
N.A.
0
P-Site Similarity:
100
100
100
66.6
N.A.
100
40
N.A.
26.6
80
N.A.
20
N.A.
66.6
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.7
38.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.5
55.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
0
8
39
8
0
0
8
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
8
31
0
0
0
8
% C
% Asp:
16
0
8
31
8
0
8
8
0
8
0
8
0
0
8
% D
% Glu:
0
0
54
16
0
0
8
0
0
0
8
8
24
54
0
% E
% Phe:
0
8
0
0
0
0
0
8
0
8
8
0
0
8
54
% F
% Gly:
0
8
0
8
8
0
0
0
0
0
16
0
0
8
0
% G
% His:
0
8
0
0
0
62
8
0
0
0
8
0
0
0
0
% H
% Ile:
0
47
0
8
8
0
0
16
0
0
0
54
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
0
8
0
8
0
8
8
0
% K
% Leu:
0
0
8
0
0
8
0
0
16
0
8
16
8
8
0
% L
% Met:
8
8
0
0
0
0
0
0
0
8
0
0
0
8
8
% M
% Asn:
54
0
8
16
8
16
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
8
0
8
8
54
0
0
39
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
8
0
0
8
8
0
0
39
0
0
% Q
% Arg:
0
8
0
0
31
0
0
0
16
0
0
8
0
0
8
% R
% Ser:
8
8
0
0
0
0
8
8
8
0
0
0
8
0
0
% S
% Thr:
8
0
8
16
0
0
8
54
0
8
0
0
8
8
16
% T
% Val:
0
0
0
8
0
0
0
0
8
8
8
8
0
0
0
% V
% Trp:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _