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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DIAPH3 All Species: 16.36
Human Site: S775 Identified Species: 32.73
UniProt: Q9NSV4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NSV4 NP_001035982.1 1193 136926 S775 N S L S Q F K S E Y S N L C E
Chimpanzee Pan troglodytes XP_509808 1253 142880 S835 N S L S Q F K S E Y S N L C E
Rhesus Macaque Macaca mulatta XP_001087983 1101 125595 E737 E I R N I I L E V N E D L L S
Dog Lupus familis XP_857344 981 113022 S621 D E T Q L A E S M I Q N L I K
Cat Felis silvestris
Mouse Mus musculus Q9Z207 1171 133668 S754 K S L S Q F R S D Y N S L C E
Rat Rattus norvegicus XP_001074393 1172 133815 S755 K S L S Q F R S D Y N S L C E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512687 1111 126766 P749 N E D L L S E P L V Q N L V K
Chicken Gallus gallus XP_417020 1172 133968 N756 N A L S K F K N E Y N N L S E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_683813 932 105075 G573 P P F P A S L G P P P P P P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48608 1091 123153 T713 I C L L R C D T D I L S S N I
Honey Bee Apis mellifera XP_395654 1140 128906 D732 K K L H F Y K D Q Y D D L T E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_800685 1168 130533 D791 K Q V Y A L K D E F N D M N E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.3 54.2 73.5 N.A. 83.4 82.9 N.A. 52.2 72.5 N.A. 43.8 N.A. 36.5 37.1 N.A. 32.6
Protein Similarity: 100 93.8 71 78 N.A. 89.6 89.2 N.A. 69.3 84.1 N.A. 58.7 N.A. 56.6 60 N.A. 52.3
P-Site Identity: 100 100 6.6 20 N.A. 66.6 66.6 N.A. 20 66.6 N.A. 0 N.A. 6.6 33.3 N.A. 20
P-Site Similarity: 100 100 20 40 N.A. 93.3 93.3 N.A. 33.3 93.3 N.A. 0 N.A. 33.3 53.3 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 17 9 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 9 0 0 0 9 0 0 0 0 0 0 0 34 0 % C
% Asp: 9 0 9 0 0 0 9 17 25 0 9 25 0 0 0 % D
% Glu: 9 17 0 0 0 0 17 9 34 0 9 0 0 0 59 % E
% Phe: 0 0 9 0 9 42 0 0 0 9 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % G
% His: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 9 0 0 9 9 0 0 0 17 0 0 0 9 9 % I
% Lys: 34 9 0 0 9 0 42 0 0 0 0 0 0 0 17 % K
% Leu: 0 0 59 17 17 9 17 0 9 0 9 0 75 9 0 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 9 0 0 % M
% Asn: 34 0 0 9 0 0 0 9 0 9 34 42 0 17 0 % N
% Pro: 9 9 0 9 0 0 0 9 9 9 9 9 9 9 9 % P
% Gln: 0 9 0 9 34 0 0 0 9 0 17 0 0 0 0 % Q
% Arg: 0 0 9 0 9 0 17 0 0 0 0 0 0 0 0 % R
% Ser: 0 34 0 42 0 17 0 42 0 0 17 25 9 9 9 % S
% Thr: 0 0 9 0 0 0 0 9 0 0 0 0 0 9 0 % T
% Val: 0 0 9 0 0 0 0 0 9 9 0 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 9 0 0 0 50 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _