KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF15
All Species:
30.61
Human Site:
T499
Identified Species:
44.89
UniProt:
Q9NS87
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NS87
NP_064627.1
1388
160160
T499
E
L
R
N
E
I
Q
T
L
R
E
Q
I
E
H
Chimpanzee
Pan troglodytes
XP_516403
1388
160229
T499
E
L
R
D
E
I
Q
T
L
R
E
Q
I
E
H
Rhesus Macaque
Macaca mulatta
XP_001114881
1388
160064
T499
E
L
R
D
E
I
Q
T
L
R
E
Q
I
E
H
Dog
Lupus familis
XP_533860
1395
160728
T508
E
L
R
D
E
I
Q
T
L
R
E
Q
I
E
H
Cat
Felis silvestris
Mouse
Mus musculus
Q6P9L6
1387
160102
T499
E
L
R
D
E
V
Q
T
L
R
E
H
V
E
H
Rat
Rattus norvegicus
Q7TSP2
1385
159522
T499
E
L
R
D
E
I
R
T
L
R
E
Q
V
E
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513181
1424
164218
T526
E
L
R
E
E
I
R
T
L
R
E
Q
M
E
Q
Chicken
Gallus gallus
Q90640
1225
138905
K447
L
Q
Q
H
A
V
C
K
L
D
L
Q
K
L
L
Frog
Xenopus laevis
Q91785
1388
159123
T504
E
L
K
E
E
I
R
T
L
K
E
Q
V
E
H
Zebra Danio
Brachydanio rerio
XP_002666969
1376
157344
L495
Q
L
Q
D
E
I
R
L
L
R
D
Q
V
E
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46867
784
88189
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P46873
699
78760
Sea Urchin
Strong. purpuratus
Q9GYZ0
1463
166571
Q509
N
L
K
K
E
I
E
Q
L
Q
E
Q
L
E
H
Poplar Tree
Populus trichocarpa
XP_002330271
2731
310584
R987
I
L
Q
K
K
L
K
R
M
Q
D
S
L
E
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_188535
2771
315043
L704
V
L
S
E
E
I
Q
L
L
Q
A
K
I
D
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
A151
E
R
I
R
D
L
L
A
P
Q
N
D
N
L
P
Conservation
Percent
Protein Identity:
100
99.4
97.6
88.3
N.A.
86
85.2
N.A.
72.6
25.4
62
48.8
N.A.
24.7
N.A.
25.3
37.3
Protein Similarity:
100
99.7
98.6
93.7
N.A.
93.4
92.8
N.A.
84.7
45.6
78.3
68.6
N.A.
36.6
N.A.
35.8
57.6
P-Site Identity:
100
93.3
93.3
93.3
N.A.
73.3
80
N.A.
73.3
13.3
66.6
53.3
N.A.
0
N.A.
0
53.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
86.6
33.3
93.3
93.3
N.A.
0
N.A.
0
80
Percent
Protein Identity:
24.1
N.A.
N.A.
24
N.A.
26.7
Protein Similarity:
37.4
N.A.
N.A.
36.4
N.A.
41.9
P-Site Identity:
13.3
N.A.
N.A.
40
N.A.
6.6
P-Site Similarity:
66.6
N.A.
N.A.
60
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
7
0
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
38
7
0
0
0
0
7
13
7
0
7
0
% D
% Glu:
57
0
0
19
69
0
7
0
0
0
57
0
0
69
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
7
0
0
57
% H
% Ile:
7
0
7
0
0
63
0
0
0
0
0
0
32
0
0
% I
% Lys:
0
0
13
13
7
0
7
7
0
7
0
7
7
0
13
% K
% Leu:
7
75
0
0
0
13
7
13
75
0
7
0
13
13
7
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
0
7
0
0
% M
% Asn:
7
0
0
7
0
0
0
0
0
0
7
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
7
% P
% Gln:
7
7
19
0
0
0
38
7
0
25
0
63
0
0
7
% Q
% Arg:
0
7
44
7
0
0
25
7
0
50
0
0
0
0
0
% R
% Ser:
0
0
7
0
0
0
0
0
0
0
0
7
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% T
% Val:
7
0
0
0
0
13
0
0
0
0
0
0
25
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _