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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMPRSS4
All Species:
0.91
Human Site:
S7
Identified Species:
2.5
UniProt:
Q9NRS4
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRS4
NP_001077416.1
437
48204
S7
_
M
L
Q
D
P
D
S
D
Q
P
L
N
S
L
Chimpanzee
Pan troglodytes
XP_001159793
435
47915
Q7
_
M
D
P
D
S
D
Q
P
L
N
S
L
D
V
Rhesus Macaque
Macaca mulatta
XP_001092969
548
60585
K118
P
L
N
S
L
D
C
K
L
S
G
S
E
Q
Q
Dog
Lupus familis
XP_546505
424
46379
P9
D
V
T
P
L
R
K
P
R
T
P
M
E
T
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCA5
435
47477
P8
M
E
S
D
S
G
Q
P
L
N
N
R
D
I
V
Rat
Rattus norvegicus
Q05511
416
44908
T8
M
A
K
E
G
G
R
T
A
P
C
C
S
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515175
519
54883
C23
G
D
N
P
D
P
A
C
E
S
P
L
T
G
E
Chicken
Gallus gallus
XP_001233789
454
49214
A25
P
S
T
F
Q
D
P
A
S
E
R
L
N
G
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001071206
430
46161
K8
M
T
A
P
K
T
Q
K
P
K
G
P
N
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
71.7
80
N.A.
76.8
31.8
N.A.
51.6
52.4
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99
75.1
87.6
N.A.
86.7
49.6
N.A.
63.3
69.5
N.A.
59
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
21.4
0
6.6
N.A.
0
0
N.A.
26.6
13.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
28.5
6.6
26.6
N.A.
13.3
20
N.A.
40
26.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
12
0
0
0
12
12
12
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
12
12
0
0
12
12
0
0
0
% C
% Asp:
12
12
12
12
34
23
23
0
12
0
0
0
12
12
0
% D
% Glu:
0
12
0
12
0
0
0
0
12
12
0
0
23
0
23
% E
% Phe:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
12
0
0
0
12
23
0
0
0
0
23
0
0
23
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% I
% Lys:
0
0
12
0
12
0
12
23
0
12
0
0
0
12
12
% K
% Leu:
0
12
12
0
23
0
0
0
23
12
0
34
12
0
12
% L
% Met:
34
23
0
0
0
0
0
0
0
0
0
12
0
0
0
% M
% Asn:
0
0
23
0
0
0
0
0
0
12
23
0
34
0
0
% N
% Pro:
23
0
0
45
0
23
12
23
23
12
34
12
0
0
12
% P
% Gln:
0
0
0
12
12
0
23
12
0
12
0
0
0
12
12
% Q
% Arg:
0
0
0
0
0
12
12
0
12
0
12
12
0
12
0
% R
% Ser:
0
12
12
12
12
12
0
12
12
23
0
23
12
12
0
% S
% Thr:
0
12
23
0
0
12
0
12
0
12
0
0
12
12
0
% T
% Val:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
23
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
23
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _