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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5E
All Species:
32.42
Human Site:
Y543
Identified Species:
64.85
UniProt:
Q9NRR6
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRR6
NP_063945.2
644
70205
Y543
F
D
I
G
K
D
T
Y
D
S
T
S
K
Q
R
Chimpanzee
Pan troglodytes
A0FI79
644
70203
Y543
F
D
I
G
K
D
T
Y
D
S
T
S
K
Q
R
Rhesus Macaque
Macaca mulatta
XP_001095203
644
70159
Y543
F
D
I
G
K
D
T
Y
D
S
T
S
K
Q
R
Dog
Lupus familis
XP_849208
665
73376
Y564
F
D
I
G
K
D
S
Y
D
T
T
S
K
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JII1
647
71896
Y546
F
D
I
G
K
D
T
Y
D
S
T
S
K
Q
R
Rat
Rattus norvegicus
Q9WVR1
647
72220
Y546
F
D
I
G
K
D
T
Y
D
S
T
S
K
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521280
342
39128
T253
K
Q
R
T
P
S
Y
T
D
R
V
V
Y
R
S
Chicken
Gallus gallus
XP_415418
659
73992
Y558
F
D
I
G
K
D
S
Y
D
T
T
S
K
Q
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648566
747
82572
F635
Y
D
P
G
S
Q
N
F
D
T
S
S
K
Q
R
Honey Bee
Apis mellifera
XP_392662
684
76969
F571
Y
D
P
G
T
Q
N
F
D
S
S
S
K
Q
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796959
989
110275
Y890
F
D
I
G
E
D
I
Y
D
T
S
A
K
A
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FUR2
646
73561
Y556
P
I
K
F
P
P
T
Y
K
Y
E
F
D
S
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.8
71.8
N.A.
76.6
75.7
N.A.
43.9
61.1
N.A.
N.A.
N.A.
32.9
32.1
N.A.
31.3
Protein Similarity:
100
99.5
98.4
79.6
N.A.
83.6
83
N.A.
49.6
71.6
N.A.
N.A.
N.A.
46.4
48.9
N.A.
43.3
P-Site Identity:
100
100
100
86.6
N.A.
100
100
N.A.
6.6
86.6
N.A.
N.A.
N.A.
46.6
53.3
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
100
N.A.
N.A.
N.A.
73.3
73.3
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
84
0
0
0
67
0
0
92
0
0
0
9
0
9
% D
% Glu:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% E
% Phe:
67
0
0
9
0
0
0
17
0
0
0
9
0
0
0
% F
% Gly:
0
0
0
84
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
67
0
0
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
9
0
9
0
59
0
0
0
9
0
0
0
84
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
17
0
17
9
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
17
0
0
0
0
0
0
0
75
0
% Q
% Arg:
0
0
9
0
0
0
0
0
0
9
0
0
0
9
84
% R
% Ser:
0
0
0
0
9
9
17
0
0
50
25
75
0
9
9
% S
% Thr:
0
0
0
9
9
0
50
9
0
34
59
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
17
0
0
0
0
0
9
75
0
9
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _