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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5E
All Species:
10
Human Site:
T54
Identified Species:
20
UniProt:
Q9NRR6
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRR6
NP_063945.2
644
70205
T54
S
P
A
L
A
C
S
T
P
A
T
P
S
G
E
Chimpanzee
Pan troglodytes
A0FI79
644
70203
T54
S
P
A
L
A
C
S
T
P
A
T
P
S
G
E
Rhesus Macaque
Macaca mulatta
XP_001095203
644
70159
T54
S
P
A
L
A
C
S
T
P
A
T
P
S
G
E
Dog
Lupus familis
XP_849208
665
73376
P71
D
V
A
P
H
L
G
P
P
P
T
N
H
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JII1
647
71896
I58
N
P
M
P
P
F
S
I
P
A
K
T
S
N
Q
Rat
Rattus norvegicus
Q9WVR1
647
72220
M58
N
S
M
P
P
L
S
M
P
A
K
P
S
N
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521280
342
39128
Chicken
Gallus gallus
XP_415418
659
73992
N72
L
P
D
E
L
K
A
N
V
K
V
K
S
I
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648566
747
82572
L93
L
K
S
Q
T
L
P
L
E
K
S
H
S
G
L
Honey Bee
Apis mellifera
XP_392662
684
76969
Q63
N
S
K
L
E
N
S
Q
H
G
S
H
T
T
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796959
989
110275
L133
N
S
T
L
K
S
S
L
F
S
S
P
L
D
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FUR2
646
73561
S79
A
D
H
G
N
N
I
S
D
G
G
V
S
V
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.8
71.8
N.A.
76.6
75.7
N.A.
43.9
61.1
N.A.
N.A.
N.A.
32.9
32.1
N.A.
31.3
Protein Similarity:
100
99.5
98.4
79.6
N.A.
83.6
83
N.A.
49.6
71.6
N.A.
N.A.
N.A.
46.4
48.9
N.A.
43.3
P-Site Identity:
100
100
100
26.6
N.A.
33.3
33.3
N.A.
0
13.3
N.A.
N.A.
N.A.
13.3
13.3
N.A.
20
P-Site Similarity:
100
100
100
33.3
N.A.
46.6
46.6
N.A.
0
20
N.A.
N.A.
N.A.
26.6
40
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
34
0
25
0
9
0
0
42
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
25
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
9
0
0
0
0
0
9
0
0
0
0
9
0
% D
% Glu:
0
0
0
9
9
0
0
0
9
0
0
0
0
0
25
% E
% Phe:
0
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
9
0
0
17
9
0
0
42
0
% G
% His:
0
0
9
0
9
0
0
0
9
0
0
17
9
0
0
% H
% Ile:
0
0
0
0
0
0
9
9
0
0
0
0
0
9
0
% I
% Lys:
0
9
9
0
9
9
0
0
0
17
17
9
0
0
9
% K
% Leu:
17
0
0
42
9
25
0
17
0
0
0
0
9
0
9
% L
% Met:
0
0
17
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
34
0
0
0
9
17
0
9
0
0
0
9
0
17
0
% N
% Pro:
0
42
0
25
17
0
9
9
50
9
0
42
0
0
9
% P
% Gln:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
25
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% R
% Ser:
25
25
9
0
0
9
59
9
0
9
25
0
67
0
0
% S
% Thr:
0
0
9
0
9
0
0
25
0
0
34
9
9
9
9
% T
% Val:
0
9
0
0
0
0
0
0
9
0
9
9
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _