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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5E
All Species:
16.67
Human Site:
T440
Identified Species:
33.33
UniProt:
Q9NRR6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRR6
NP_063945.2
644
70205
T440
A
E
R
L
L
D
Y
T
R
T
V
Q
A
L
V
Chimpanzee
Pan troglodytes
A0FI79
644
70203
T440
A
E
R
L
L
D
Y
T
R
T
V
Q
A
L
A
Rhesus Macaque
Macaca mulatta
XP_001095203
644
70159
T440
A
E
R
L
L
D
Y
T
R
T
V
Q
A
L
A
Dog
Lupus familis
XP_849208
665
73376
S461
S
E
R
L
L
D
Y
S
R
T
I
Q
G
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9JII1
647
71896
S443
A
E
R
L
L
D
Y
S
R
T
I
Q
A
L
A
Rat
Rattus norvegicus
Q9WVR1
647
72220
N443
A
E
R
L
L
D
Y
N
R
T
I
Q
A
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521280
342
39128
F167
S
S
D
V
T
T
R
F
D
E
V
F
W
F
G
Chicken
Gallus gallus
XP_415418
659
73992
N455
N
E
R
K
L
D
Y
N
K
T
I
Q
A
L
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648566
747
82572
K531
K
E
R
V
S
D
V
K
R
I
I
N
A
L
D
Honey Bee
Apis mellifera
XP_392662
684
76969
K471
K
E
R
V
N
D
I
K
R
I
V
R
N
L
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796959
989
110275
W636
S
S
P
D
I
A
E
W
E
I
R
L
Q
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FUR2
646
73561
D469
A
E
Q
R
R
N
A
D
V
Y
E
I
I
R
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.8
71.8
N.A.
76.6
75.7
N.A.
43.9
61.1
N.A.
N.A.
N.A.
32.9
32.1
N.A.
31.3
Protein Similarity:
100
99.5
98.4
79.6
N.A.
83.6
83
N.A.
49.6
71.6
N.A.
N.A.
N.A.
46.4
48.9
N.A.
43.3
P-Site Identity:
100
93.3
93.3
66.6
N.A.
80
80
N.A.
6.6
60
N.A.
N.A.
N.A.
40
40
N.A.
0
P-Site Similarity:
100
93.3
93.3
86.6
N.A.
93.3
86.6
N.A.
20
73.3
N.A.
N.A.
N.A.
53.3
53.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
0
0
0
9
9
0
0
0
0
0
59
0
42
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
9
0
75
0
9
9
0
0
0
0
0
17
% D
% Glu:
0
84
0
0
0
0
9
0
9
9
9
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
0
9
0
9
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
9
0
0
25
42
9
9
0
0
% I
% Lys:
17
0
0
9
0
0
0
17
9
0
0
0
0
0
0
% K
% Leu:
0
0
0
50
59
0
0
0
0
0
0
9
0
75
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
9
9
0
17
0
0
0
9
9
0
0
% N
% Pro:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
0
59
9
0
0
% Q
% Arg:
0
0
75
9
9
0
9
0
67
0
9
9
0
9
9
% R
% Ser:
25
17
0
0
9
0
0
17
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
9
9
0
25
0
59
0
0
0
0
17
% T
% Val:
0
0
0
25
0
0
9
0
9
0
42
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
0
% W
% Tyr:
0
0
0
0
0
0
59
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _