KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5E
All Species:
13.94
Human Site:
S241
Identified Species:
27.88
UniProt:
Q9NRR6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRR6
NP_063945.2
644
70205
S241
L
G
P
G
R
P
R
S
P
L
A
C
D
D
C
Chimpanzee
Pan troglodytes
A0FI79
644
70203
S241
L
G
P
G
R
P
R
S
P
L
A
C
D
D
C
Rhesus Macaque
Macaca mulatta
XP_001095203
644
70159
S241
L
G
P
G
R
P
R
S
P
L
A
C
D
D
C
Dog
Lupus familis
XP_849208
665
73376
G262
F
R
A
H
S
S
L
G
P
G
R
P
P
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9JII1
647
71896
R244
N
L
G
P
S
R
P
R
S
P
L
A
G
D
D
Rat
Rattus norvegicus
Q9WVR1
647
72220
S244
L
G
P
S
R
P
R
S
P
L
A
G
D
D
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521280
342
39128
Chicken
Gallus gallus
XP_415418
659
73992
N256
S
D
T
R
L
H
G
N
G
I
V
Y
D
N
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648566
747
82572
T332
F
M
S
H
E
N
M
T
L
Q
R
Q
G
S
G
Honey Bee
Apis mellifera
XP_392662
684
76969
S272
K
K
K
E
R
H
Q
S
Q
T
T
G
A
S
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796959
989
110275
G529
S
E
M
S
V
L
S
G
G
S
M
S
E
T
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FUR2
646
73561
Q270
L
A
L
D
S
N
P
Q
I
V
G
S
E
G
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.8
71.8
N.A.
76.6
75.7
N.A.
43.9
61.1
N.A.
N.A.
N.A.
32.9
32.1
N.A.
31.3
Protein Similarity:
100
99.5
98.4
79.6
N.A.
83.6
83
N.A.
49.6
71.6
N.A.
N.A.
N.A.
46.4
48.9
N.A.
43.3
P-Site Identity:
100
100
100
6.6
N.A.
6.6
80
N.A.
0
13.3
N.A.
N.A.
N.A.
0
13.3
N.A.
0
P-Site Similarity:
100
100
100
6.6
N.A.
6.6
80
N.A.
0
33.3
N.A.
N.A.
N.A.
6.6
20
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
0
0
0
0
0
0
34
9
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
25
0
0
34
% C
% Asp:
0
9
0
9
0
0
0
0
0
0
0
0
42
42
9
% D
% Glu:
0
9
0
9
9
0
0
0
0
0
0
0
17
0
0
% E
% Phe:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
34
9
25
0
0
9
17
17
9
9
17
17
9
9
% G
% His:
0
0
0
17
0
17
0
0
0
0
0
0
0
0
9
% H
% Ile:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% I
% Lys:
9
9
9
0
0
0
0
0
0
0
0
0
0
0
9
% K
% Leu:
42
9
9
0
9
9
9
0
9
34
9
0
0
0
0
% L
% Met:
0
9
9
0
0
0
9
0
0
0
9
0
0
0
9
% M
% Asn:
9
0
0
0
0
17
0
9
0
0
0
0
0
9
9
% N
% Pro:
0
0
34
9
0
34
17
0
42
9
0
9
9
0
9
% P
% Gln:
0
0
0
0
0
0
9
9
9
9
0
9
0
0
0
% Q
% Arg:
0
9
0
9
42
9
34
9
0
0
17
0
0
0
0
% R
% Ser:
17
0
9
17
25
9
9
42
9
9
0
17
0
25
0
% S
% Thr:
0
0
9
0
0
0
0
9
0
9
9
0
0
9
0
% T
% Val:
0
0
0
0
9
0
0
0
0
9
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _