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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5E
All Species:
10.61
Human Site:
S187
Identified Species:
21.21
UniProt:
Q9NRR6
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRR6
NP_063945.2
644
70205
S187
G
S
S
P
R
L
P
S
L
L
P
P
R
P
P
Chimpanzee
Pan troglodytes
A0FI79
644
70203
S187
G
S
S
P
R
L
P
S
L
L
P
P
R
P
P
Rhesus Macaque
Macaca mulatta
XP_001095203
644
70159
S187
G
S
S
P
R
L
P
S
L
L
P
P
R
P
P
Dog
Lupus familis
XP_849208
665
73376
L208
I
S
T
S
L
D
L
L
H
R
D
G
A
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9JII1
647
71896
A190
G
G
P
P
S
R
L
A
S
L
H
A
S
H
T
Rat
Rattus norvegicus
Q9WVR1
647
72220
S190
V
G
H
S
R
L
A
S
L
R
A
T
H
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521280
342
39128
Chicken
Gallus gallus
XP_415418
659
73992
I202
S
K
P
R
L
S
Q
I
M
P
A
R
P
L
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648566
747
82572
G278
R
L
K
L
Y
P
P
G
Q
E
L
P
P
L
Q
Honey Bee
Apis mellifera
XP_392662
684
76969
Q218
N
V
P
A
Y
L
R
Q
R
L
I
H
R
R
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796959
989
110275
P475
D
A
L
R
A
A
S
P
T
D
S
L
R
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FUR2
646
73561
N216
P
I
L
A
Q
E
A
N
S
I
I
S
H
V
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.8
71.8
N.A.
76.6
75.7
N.A.
43.9
61.1
N.A.
N.A.
N.A.
32.9
32.1
N.A.
31.3
Protein Similarity:
100
99.5
98.4
79.6
N.A.
83.6
83
N.A.
49.6
71.6
N.A.
N.A.
N.A.
46.4
48.9
N.A.
43.3
P-Site Identity:
100
100
100
6.6
N.A.
20
33.3
N.A.
0
6.6
N.A.
N.A.
N.A.
13.3
20
N.A.
6.6
P-Site Similarity:
100
100
100
13.3
N.A.
26.6
33.3
N.A.
0
13.3
N.A.
N.A.
N.A.
13.3
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
17
9
9
17
9
0
0
17
9
9
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
9
0
0
0
9
9
0
0
0
0
% D
% Glu:
0
0
0
0
0
9
0
0
0
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
34
17
0
0
0
0
0
9
0
0
0
9
0
0
9
% G
% His:
0
0
9
0
0
0
0
0
9
0
9
9
17
9
0
% H
% Ile:
9
9
0
0
0
0
0
9
0
9
17
0
0
0
0
% I
% Lys:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
17
9
17
42
17
9
34
42
9
9
0
17
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% M
% Asn:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
9
0
25
34
0
9
34
9
0
9
25
34
17
25
42
% P
% Gln:
0
0
0
0
9
0
9
9
9
0
0
0
0
0
9
% Q
% Arg:
9
0
0
17
34
9
9
0
9
17
0
9
42
9
0
% R
% Ser:
9
34
25
17
9
9
9
34
17
0
9
9
9
0
9
% S
% Thr:
0
0
9
0
0
0
0
0
9
0
0
9
0
9
9
% T
% Val:
9
9
0
0
0
0
0
0
0
0
0
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _