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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LATS2
All Species:
8.48
Human Site:
S543
Identified Species:
13.33
UniProt:
Q9NRM7
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRM7
NP_055387.2
1088
120136
S543
L
C
A
G
M
E
Q
S
L
R
A
G
P
N
E
Chimpanzee
Pan troglodytes
XP_001149147
1088
120220
S543
L
C
A
G
M
E
Q
S
L
R
A
G
P
N
E
Rhesus Macaque
Macaca mulatta
XP_001090321
809
89257
I327
T
A
V
T
A
A
H
I
L
H
P
V
K
S
V
Dog
Lupus familis
XP_534537
1097
121903
R552
T
G
L
E
Q
S
L
R
G
S
Q
A
A
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q7TSJ6
1042
115454
Q501
S
L
C
T
S
V
Q
Q
S
L
R
G
G
T
E
Rat
Rattus norvegicus
NP_001100737
1042
115346
Q501
R
L
C
T
G
V
E
Q
S
L
R
G
G
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506215
1121
123969
S570
P
Y
E
P
L
P
K
S
R
E
D
Q
P
C
V
Chicken
Gallus gallus
XP_417143
1127
126652
T582
L
R
V
V
P
S
S
T
C
N
K
A
E
E
N
Frog
Xenopus laevis
NP_001087838
1118
125984
K566
E
S
G
L
K
S
S
K
E
D
A
A
G
V
S
Zebra Danio
Brachydanio rerio
NP_001121728
1078
119704
S521
A
T
G
R
T
I
Q
S
S
S
V
G
K
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NBK5
463
53314
Honey Bee
Apis mellifera
XP_395146
1137
124999
N616
N
G
G
N
N
N
N
N
N
N
N
N
N
N
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795100
1199
133231
V656
T
R
S
E
S
P
L
V
R
P
P
S
L
I
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53894
756
86927
L274
Y
F
E
R
R
P
D
L
L
T
K
G
T
Q
D
Red Bread Mold
Neurospora crassa
P38679
598
67999
S116
Q
T
Y
G
N
Y
L
S
A
P
M
P
S
N
T
Conservation
Percent
Protein Identity:
100
99.4
70.5
86.6
N.A.
82.5
82.9
N.A.
48.7
75.6
47.8
63.5
N.A.
22.5
40.8
N.A.
38.6
Protein Similarity:
100
99.7
71.2
89.8
N.A.
86.5
86.9
N.A.
61
83.2
58.7
72.9
N.A.
31.4
52.7
N.A.
52
P-Site Identity:
100
100
6.6
0
N.A.
20
13.3
N.A.
13.3
6.6
6.6
26.6
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
100
13.3
0
N.A.
20
20
N.A.
26.6
13.3
6.6
26.6
N.A.
0
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.1
24.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
36.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
14
0
7
7
0
0
7
0
20
20
7
0
0
% A
% Cys:
0
14
14
0
0
0
0
0
7
0
0
0
0
7
0
% C
% Asp:
0
0
0
0
0
0
7
0
0
7
7
0
0
0
7
% D
% Glu:
7
0
14
14
0
14
7
0
7
7
0
0
7
14
34
% E
% Phe:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
14
20
20
7
0
0
0
7
0
0
40
20
0
0
% G
% His:
0
0
0
0
0
0
7
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
7
0
7
0
0
0
0
0
7
0
% I
% Lys:
0
0
0
0
7
0
7
7
0
0
14
0
14
0
0
% K
% Leu:
20
14
7
7
7
0
20
7
27
14
0
0
7
0
0
% L
% Met:
0
0
0
0
14
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
7
0
0
7
14
7
7
7
7
14
7
7
7
27
14
% N
% Pro:
7
0
0
7
7
20
0
0
0
14
14
7
20
0
7
% P
% Gln:
7
0
0
0
7
0
27
14
0
0
7
7
0
14
0
% Q
% Arg:
7
14
0
14
7
0
0
7
14
14
14
0
0
0
0
% R
% Ser:
7
7
7
0
14
20
14
34
20
14
0
7
7
7
14
% S
% Thr:
20
14
0
20
7
0
0
7
0
7
0
0
7
14
7
% T
% Val:
0
0
14
7
0
14
0
7
0
0
7
7
0
7
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
7
7
0
0
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _