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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LATS2
All Species:
24.24
Human Site:
S446
Identified Species:
38.1
UniProt:
Q9NRM7
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRM7
NP_055387.2
1088
120136
S446
H
I
L
H
P
V
K
S
V
R
V
L
R
P
E
Chimpanzee
Pan troglodytes
XP_001149147
1088
120220
S446
H
I
L
H
P
V
K
S
V
R
V
L
R
P
E
Rhesus Macaque
Macaca mulatta
XP_001090321
809
89257
A260
S
V
Q
Q
W
P
A
A
T
L
A
R
R
D
S
Dog
Lupus familis
XP_534537
1097
121903
S460
H
I
L
H
P
V
K
S
V
R
V
M
R
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q7TSJ6
1042
115454
P424
V
R
V
L
R
P
E
P
Q
T
A
V
G
P
S
Rat
Rattus norvegicus
NP_001100737
1042
115346
P423
V
R
V
L
R
P
E
P
Q
T
A
V
G
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506215
1121
123969
S491
P
I
Q
Q
P
V
K
S
M
R
V
L
K
P
E
Chicken
Gallus gallus
XP_417143
1127
126652
S485
H
I
L
Q
P
V
K
S
M
R
V
M
R
P
E
Frog
Xenopus laevis
NP_001087838
1118
125984
S493
P
I
Q
Q
P
V
K
S
I
R
V
L
K
P
E
Zebra Danio
Brachydanio rerio
NP_001121728
1078
119704
S431
P
I
Q
P
P
V
K
S
I
R
V
M
R
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NBK5
463
53314
Honey Bee
Apis mellifera
XP_395146
1137
124999
N544
N
C
I
S
T
I
D
N
N
T
T
L
R
S
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795100
1199
133231
V584
H
L
K
V
P
V
P
V
P
A
A
V
S
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53894
756
86927
A207
V
Q
Q
Q
L
S
Q
A
Q
Q
Q
N
S
R
Q
Red Bread Mold
Neurospora crassa
P38679
598
67999
N49
A
G
G
S
Q
Q
Y
N
Q
A
Y
A
Q
S
G
Conservation
Percent
Protein Identity:
100
99.4
70.5
86.6
N.A.
82.5
82.9
N.A.
48.7
75.6
47.8
63.5
N.A.
22.5
40.8
N.A.
38.6
Protein Similarity:
100
99.7
71.2
89.8
N.A.
86.5
86.9
N.A.
61
83.2
58.7
72.9
N.A.
31.4
52.7
N.A.
52
P-Site Identity:
100
100
6.6
93.3
N.A.
6.6
6.6
N.A.
66.6
80
66.6
66.6
N.A.
0
13.3
N.A.
20
P-Site Similarity:
100
100
20
100
N.A.
26.6
26.6
N.A.
80
93.3
80
80
N.A.
0
40
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.1
24.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
36.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
7
14
0
14
27
7
0
0
0
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
7
0
0
0
0
0
0
7
0
% D
% Glu:
0
0
0
0
0
0
14
0
0
0
0
0
0
0
47
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
7
0
0
0
0
0
0
0
0
0
14
0
7
% G
% His:
34
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
47
7
0
0
7
0
0
14
0
0
0
0
0
0
% I
% Lys:
0
0
7
0
0
0
47
0
0
0
0
0
14
0
0
% K
% Leu:
0
7
27
14
7
0
0
0
0
7
0
34
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
14
0
0
20
0
0
0
% M
% Asn:
7
0
0
0
0
0
0
14
7
0
0
7
0
0
0
% N
% Pro:
20
0
0
7
54
20
7
14
7
0
0
0
0
60
0
% P
% Gln:
0
7
34
34
7
7
7
0
27
7
7
0
7
0
7
% Q
% Arg:
0
14
0
0
14
0
0
0
0
47
0
7
47
7
0
% R
% Ser:
7
0
0
14
0
7
0
47
0
0
0
0
14
20
27
% S
% Thr:
0
0
0
0
7
0
0
0
7
20
7
0
0
0
7
% T
% Val:
20
7
14
7
0
54
0
7
20
0
47
20
0
0
0
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _