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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LATS2
All Species:
5.45
Human Site:
S335
Identified Species:
8.57
UniProt:
Q9NRM7
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRM7
NP_055387.2
1088
120136
S335
L
H
V
L
G
S
R
S
Q
V
F
A
S
D
S
Chimpanzee
Pan troglodytes
XP_001149147
1088
120220
S335
L
H
V
L
G
S
R
S
Q
V
F
A
S
D
S
Rhesus Macaque
Macaca mulatta
XP_001090321
809
89257
R158
P
L
G
Y
G
V
Q
R
S
P
S
F
Q
G
K
Dog
Lupus familis
XP_534537
1097
121903
G343
V
H
M
L
G
S
R
G
Q
V
F
T
S
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q7TSJ6
1042
115454
G319
L
H
V
L
G
T
R
G
P
T
F
T
G
E
S
Rat
Rattus norvegicus
NP_001100737
1042
115346
G318
L
H
V
L
G
T
R
G
P
T
F
T
G
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506215
1121
123969
P388
Q
T
G
V
P
A
A
P
S
P
Y
A
N
G
T
Chicken
Gallus gallus
XP_417143
1127
126652
F366
V
I
S
R
G
P
A
F
G
N
D
F
S
D
S
Frog
Xenopus laevis
NP_001087838
1118
125984
L389
V
Q
S
G
G
G
P
L
S
S
N
A
Y
G
T
Zebra Danio
Brachydanio rerio
NP_001121728
1078
119704
A324
P
P
G
V
A
P
G
A
M
G
G
E
F
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NBK5
463
53314
Honey Bee
Apis mellifera
XP_395146
1137
124999
S349
S
Q
Q
D
Y
R
K
S
P
S
S
G
I
Y
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795100
1199
133231
Q476
A
G
H
I
G
G
Q
Q
Q
R
G
G
T
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53894
756
86927
Q105
N
N
Y
A
A
S
N
Q
M
I
N
T
P
P
P
Red Bread Mold
Neurospora crassa
P38679
598
67999
Conservation
Percent
Protein Identity:
100
99.4
70.5
86.6
N.A.
82.5
82.9
N.A.
48.7
75.6
47.8
63.5
N.A.
22.5
40.8
N.A.
38.6
Protein Similarity:
100
99.7
71.2
89.8
N.A.
86.5
86.9
N.A.
61
83.2
58.7
72.9
N.A.
31.4
52.7
N.A.
52
P-Site Identity:
100
100
6.6
73.3
N.A.
53.3
60
N.A.
6.6
26.6
13.3
0
N.A.
0
13.3
N.A.
13.3
P-Site Similarity:
100
100
13.3
86.6
N.A.
66.6
66.6
N.A.
40
33.3
26.6
13.3
N.A.
0
20
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.1
24.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
36.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
14
7
14
7
0
0
0
27
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
0
0
0
0
0
7
0
0
34
7
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
7
0
7
0
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
34
14
7
0
0
% F
% Gly:
0
7
20
7
60
14
7
20
7
7
14
14
14
20
0
% G
% His:
0
34
7
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
7
0
0
0
0
0
7
0
0
7
0
0
% I
% Lys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
7
% K
% Leu:
27
7
0
34
0
0
0
7
0
0
0
0
0
0
0
% L
% Met:
0
0
7
0
0
0
0
0
14
0
0
0
0
0
0
% M
% Asn:
7
7
0
0
0
0
7
0
0
7
14
0
7
0
0
% N
% Pro:
14
7
0
0
7
14
7
7
20
14
0
0
7
14
7
% P
% Gln:
7
14
7
0
0
0
14
14
27
0
0
0
7
0
0
% Q
% Arg:
0
0
0
7
0
7
34
7
0
7
0
0
0
0
0
% R
% Ser:
7
0
14
0
0
27
0
20
20
14
14
0
27
7
47
% S
% Thr:
0
7
0
0
0
14
0
0
0
14
0
27
7
0
20
% T
% Val:
20
0
27
14
0
7
0
0
0
20
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
7
7
0
0
0
0
0
7
0
7
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _