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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LATS2 All Species: 13.03
Human Site: S1059 Identified Species: 20.48
UniProt: Q9NRM7 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NRM7 NP_055387.2 1088 120136 S1059 P F R C P K P S G A E A S Q A
Chimpanzee Pan troglodytes XP_001149147 1088 120220 S1059 P F R C P K P S G A E A S Q A
Rhesus Macaque Macaca mulatta XP_001090321 809 89257 S781 T Q L C D W W S V G V I L F E
Dog Lupus familis XP_534537 1097 121903 S1068 P F R C P K P S G A D A S Q A
Cat Felis silvestris
Mouse Mus musculus Q7TSJ6 1042 115454 C1013 D N G Y P F R C P K P S E P A
Rat Rattus norvegicus NP_001100737 1042 115346 C1013 D N G Y P F R C P K P S E P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506215 1121 123969 P1086 Y P Y N Y P K P I E Y E Y S S
Chicken Gallus gallus XP_417143 1127 126652 S1098 P F R Y P K P S G M E V G Q S
Frog Xenopus laevis NP_001087838 1118 125984 P1082 H P Y N Y P K P F R Y D Y D D
Zebra Danio Brachydanio rerio NP_001121728 1078 119704 K1037 G C P F R Y P K P L E A T Q S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NBK5 463 53314 A435 V S L E I P S A P I P Q G G E
Honey Bee Apis mellifera XP_395146 1137 124999 F1108 H G F F E F T F R R F F D D G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795100 1199 133231 I1168 P Y P M P I D I D S S P G P G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53894 756 86927 G728 R E Q M T K Q G G S A P V K E
Red Bread Mold Neurospora crassa P38679 598 67999 A570 Q Q A A R G A A A P A Q Q E E
Conservation
Percent
Protein Identity: 100 99.4 70.5 86.6 N.A. 82.5 82.9 N.A. 48.7 75.6 47.8 63.5 N.A. 22.5 40.8 N.A. 38.6
Protein Similarity: 100 99.7 71.2 89.8 N.A. 86.5 86.9 N.A. 61 83.2 58.7 72.9 N.A. 31.4 52.7 N.A. 52
P-Site Identity: 100 100 13.3 93.3 N.A. 13.3 13.3 N.A. 0 66.6 0 26.6 N.A. 0 0 N.A. 13.3
P-Site Similarity: 100 100 13.3 100 N.A. 20 20 N.A. 6.6 73.3 0 40 N.A. 6.6 0 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28.1 24.5
Protein Similarity: N.A. N.A. N.A. N.A. 42.1 36.4
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 0
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 7 0 0 7 14 7 20 14 27 0 0 34 % A
% Cys: 0 7 0 27 0 0 0 14 0 0 0 0 0 0 0 % C
% Asp: 14 0 0 0 7 0 7 0 7 0 7 7 7 14 7 % D
% Glu: 0 7 0 7 7 0 0 0 0 7 27 7 14 7 27 % E
% Phe: 0 27 7 14 0 20 0 7 7 0 7 7 0 7 0 % F
% Gly: 7 7 14 0 0 7 0 7 34 7 0 0 20 7 14 % G
% His: 14 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 7 7 0 7 7 7 0 7 0 0 0 % I
% Lys: 0 0 0 0 0 34 14 7 0 14 0 0 0 7 0 % K
% Leu: 0 0 14 0 0 0 0 0 0 7 0 0 7 0 0 % L
% Met: 0 0 0 14 0 0 0 0 0 7 0 0 0 0 0 % M
% Asn: 0 14 0 14 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 34 14 14 0 47 20 34 14 27 7 20 14 0 20 0 % P
% Gln: 7 14 7 0 0 0 7 0 0 0 0 14 7 34 0 % Q
% Arg: 7 0 27 0 14 0 14 0 7 14 0 0 0 0 0 % R
% Ser: 0 7 0 0 0 0 7 34 0 14 7 14 20 7 20 % S
% Thr: 7 0 0 0 7 0 7 0 0 0 0 0 7 0 0 % T
% Val: 7 0 0 0 0 0 0 0 7 0 7 7 7 0 0 % V
% Trp: 0 0 0 0 0 7 7 0 0 0 0 0 0 0 0 % W
% Tyr: 7 7 14 20 14 7 0 0 0 0 14 0 14 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _