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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMYD2
All Species:
25.45
Human Site:
T44
Identified Species:
43.08
UniProt:
Q9NRG4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRG4
NP_064582.2
433
49688
T44
P
A
Y
A
Y
V
L
T
V
N
E
R
G
N
H
Chimpanzee
Pan troglodytes
XP_514316
454
52196
C41
D
P
L
A
Y
T
V
C
K
G
S
R
G
V
V
Rhesus Macaque
Macaca mulatta
XP_001106482
433
49665
T44
P
A
Y
A
Y
V
L
T
V
N
E
R
G
N
H
Dog
Lupus familis
XP_537149
432
49720
E43
C
D
Y
M
Y
I
L
E
Y
Q
L
P
G
V
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8R5A0
433
49548
T44
P
A
Y
A
C
V
L
T
V
G
E
R
G
H
H
Rat
Rattus norvegicus
Q7M6Z3
433
49630
T44
P
A
Y
A
C
V
L
T
V
G
E
R
G
H
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510161
439
49949
M50
L
T
V
V
M
G
L
M
V
L
T
G
Q
I
A
Chicken
Gallus gallus
XP_419420
436
49919
T47
P
A
Y
T
A
V
L
T
V
S
E
R
G
S
H
Frog
Xenopus laevis
NP_001085986
430
49101
T42
P
A
Y
T
Y
V
L
T
D
N
E
R
G
N
H
Zebra Danio
Brachydanio rerio
NP_001013568
435
50045
T44
P
A
Y
A
Y
V
L
T
V
N
E
R
G
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46040
462
52138
L80
R
D
I
A
A
G
E
L
I
F
Q
E
R
A
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09415
429
48527
S40
M
A
E
L
K
K
C
S
A
C
R
R
L
A
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001131420
482
54569
N52
E
P
Y
A
S
T
P
N
K
I
L
V
G
S
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q7XJS0
480
54809
N48
K
P
Y
I
C
V
P
N
N
T
S
S
E
S
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32.8
99
92.6
N.A.
93.3
93.5
N.A.
80.6
85.5
78.7
75.4
N.A.
20.5
N.A.
22.6
N.A.
Protein Similarity:
100
53.7
99
94.2
N.A.
96.5
97
N.A.
85.8
94
88.2
87.3
N.A.
35
N.A.
42.7
N.A.
P-Site Identity:
100
26.6
100
33.3
N.A.
80
80
N.A.
13.3
73.3
86.6
86.6
N.A.
6.6
N.A.
13.3
N.A.
P-Site Similarity:
100
33.3
100
40
N.A.
86.6
86.6
N.A.
13.3
86.6
86.6
86.6
N.A.
20
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
29.8
N.A.
25.8
N.A.
N.A.
Protein Similarity:
N.A.
46.4
N.A.
45.8
N.A.
N.A.
P-Site Identity:
N.A.
20
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
58
0
58
15
0
0
0
8
0
0
0
0
15
8
% A
% Cys:
8
0
0
0
22
0
8
8
0
8
0
0
0
0
0
% C
% Asp:
8
15
0
0
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
8
0
8
0
0
0
8
8
0
0
50
8
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
15
0
0
0
22
0
8
72
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
50
% H
% Ile:
0
0
8
8
0
8
0
0
8
8
0
0
0
8
0
% I
% Lys:
8
0
0
0
8
8
0
0
15
0
0
0
0
0
0
% K
% Leu:
8
0
8
8
0
0
65
8
0
8
15
0
8
0
8
% L
% Met:
8
0
0
8
8
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
15
8
29
0
0
0
22
0
% N
% Pro:
50
22
0
0
0
0
15
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
8
0
8
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
8
65
8
0
15
% R
% Ser:
0
0
0
0
8
0
0
8
0
8
15
8
0
22
8
% S
% Thr:
0
8
0
15
0
15
0
50
0
8
8
0
0
0
0
% T
% Val:
0
0
8
8
0
58
8
0
50
0
0
8
0
15
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
72
0
43
0
0
0
8
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _