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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SMYD2 All Species: 36.36
Human Site: S192 Identified Species: 61.54
UniProt: Q9NRG4 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NRG4 NP_064582.2 433 49688 S192 T I E D E E L S H L G S A I F
Chimpanzee Pan troglodytes XP_514316 454 52196 Q217 T I C N A E M Q E V G V G L Y
Rhesus Macaque Macaca mulatta XP_001106482 433 49665 S192 T I E D E E L S H L G S A I F
Dog Lupus familis XP_537149 432 49720 S191 T I E D E E L S H L G S A I F
Cat Felis silvestris
Mouse Mus musculus Q8R5A0 433 49548 S192 T I E D E E L S H L G S A I F
Rat Rattus norvegicus Q7M6Z3 433 49630 S192 T I E D E E L S H L G S A I F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510161 439 49949 S198 T I E D E E L S H L G S A I F
Chicken Gallus gallus XP_419420 436 49919 S195 T I E D E E L S H L G S A I F
Frog Xenopus laevis NP_001085986 430 49101 S190 T I E D E E L S H L G S A I F
Zebra Danio Brachydanio rerio NP_001013568 435 50045 S192 T I E D E E L S H L G S A L F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O46040 462 52138 E237 P C R S G G H E T L L R G L F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09415 429 48527 V186 S C K P L T R V C Y R N R T A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001131420 482 54569 R203 T I C D P E L R P L G T G L Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q7XJS0 480 54809 R199 S I C D S E L R P Q G I G L F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 32.8 99 92.6 N.A. 93.3 93.5 N.A. 80.6 85.5 78.7 75.4 N.A. 20.5 N.A. 22.6 N.A.
Protein Similarity: 100 53.7 99 94.2 N.A. 96.5 97 N.A. 85.8 94 88.2 87.3 N.A. 35 N.A. 42.7 N.A.
P-Site Identity: 100 26.6 100 100 N.A. 100 100 N.A. 100 100 100 93.3 N.A. 13.3 N.A. 0 N.A.
P-Site Similarity: 100 60 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 20 N.A. 20 N.A.
Percent
Protein Identity: N.A. 29.8 N.A. 25.8 N.A. N.A.
Protein Similarity: N.A. 46.4 N.A. 45.8 N.A. N.A.
P-Site Identity: N.A. 46.6 N.A. 40 N.A. N.A.
P-Site Similarity: N.A. 66.6 N.A. 53.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 0 0 0 0 0 65 0 8 % A
% Cys: 0 15 22 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 0 79 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 65 0 65 86 0 8 8 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 79 % F
% Gly: 0 0 0 0 8 8 0 0 0 0 86 0 29 0 0 % G
% His: 0 0 0 0 0 0 8 0 65 0 0 0 0 0 0 % H
% Ile: 0 86 0 0 0 0 0 0 0 0 0 8 0 58 0 % I
% Lys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 8 0 79 0 0 79 8 0 0 36 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 0 0 0 0 8 0 0 0 % N
% Pro: 8 0 0 8 8 0 0 0 15 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 8 15 0 0 8 8 8 0 0 % R
% Ser: 15 0 0 8 8 0 0 65 0 0 0 65 0 0 0 % S
% Thr: 79 0 0 0 0 8 0 0 8 0 0 8 0 8 0 % T
% Val: 0 0 0 0 0 0 0 8 0 8 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _