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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SMYD2 All Species: 29.09
Human Site: S151 Identified Species: 49.23
UniProt: Q9NRG4 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NRG4 NP_064582.2 433 49688 S151 E K K D L I Q S D I A A L H H
Chimpanzee Pan troglodytes XP_514316 454 52196 A176 F D L F E A F A K R W S L A M
Rhesus Macaque Macaca mulatta XP_001106482 433 49665 S151 E K K D L I Q S D I A A L H H
Dog Lupus familis XP_537149 432 49720 S150 E K K D L I Q S D I A A L H H
Cat Felis silvestris
Mouse Mus musculus Q8R5A0 433 49548 S151 E K K D L I Q S D I A A L H Q
Rat Rattus norvegicus Q7M6Z3 433 49630 S151 E K K D L I Q S D I A A L H Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510161 439 49949 S157 E K R E L I Q S D I A A L H H
Chicken Gallus gallus XP_419420 436 49919 N154 E K R E L I Q N D I A A L H H
Frog Xenopus laevis NP_001085986 430 49101 N149 E K K E L I E N D I S A L H R
Zebra Danio Brachydanio rerio NP_001013568 435 50045 T151 E K N E M N D T D I A A L H H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O46040 462 52138 Q196 A Y R R E I I Q A A Q C F R N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09415 429 48527 L145 P D R D L I K L I F Q K V S I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001131420 482 54569 Y162 D E N Q L V L Y A Q M A N L V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q7XJS0 480 54809 Y158 D E K Q M L L Y A Q M A N L V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 32.8 99 92.6 N.A. 93.3 93.5 N.A. 80.6 85.5 78.7 75.4 N.A. 20.5 N.A. 22.6 N.A.
Protein Similarity: 100 53.7 99 94.2 N.A. 96.5 97 N.A. 85.8 94 88.2 87.3 N.A. 35 N.A. 42.7 N.A.
P-Site Identity: 100 6.6 100 100 N.A. 93.3 93.3 N.A. 86.6 80 66.6 60 N.A. 6.6 N.A. 20 N.A.
P-Site Similarity: 100 20 100 100 N.A. 93.3 93.3 N.A. 100 100 93.3 80 N.A. 20 N.A. 40 N.A.
Percent
Protein Identity: N.A. 29.8 N.A. 25.8 N.A. N.A.
Protein Similarity: N.A. 46.4 N.A. 45.8 N.A. N.A.
P-Site Identity: N.A. 13.3 N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. 33.3 N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 8 0 8 22 8 58 79 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 15 15 0 43 0 0 8 0 65 0 0 0 0 0 0 % D
% Glu: 65 15 0 29 15 0 8 0 0 0 0 0 0 0 0 % E
% Phe: 8 0 0 8 0 0 8 0 0 8 0 0 8 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 65 43 % H
% Ile: 0 0 0 0 0 72 8 0 8 65 0 0 0 0 8 % I
% Lys: 0 65 50 0 0 0 8 0 8 0 0 8 0 0 0 % K
% Leu: 0 0 8 0 72 8 15 8 0 0 0 0 72 15 0 % L
% Met: 0 0 0 0 15 0 0 0 0 0 15 0 0 0 8 % M
% Asn: 0 0 15 0 0 8 0 15 0 0 0 0 15 0 8 % N
% Pro: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 15 0 0 50 8 0 15 15 0 0 0 15 % Q
% Arg: 0 0 29 8 0 0 0 0 0 8 0 0 0 8 8 % R
% Ser: 0 0 0 0 0 0 0 43 0 0 8 8 0 8 0 % S
% Thr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 8 0 0 0 0 0 0 8 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 15 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _