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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTPS2
All Species:
22.12
Human Site:
S576
Identified Species:
37.44
UniProt:
Q9NRF8
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRF8
NP_001137474.1
586
65678
S576
D
A
S
D
D
S
F
S
E
P
R
I
A
E
L
Chimpanzee
Pan troglodytes
XP_520953
586
65363
S576
D
A
S
D
D
S
F
S
E
P
R
I
A
E
L
Rhesus Macaque
Macaca mulatta
XP_001117012
616
69695
S606
D
A
S
D
D
S
F
S
E
P
R
I
A
E
L
Dog
Lupus familis
XP_537968
586
65447
S576
D
A
S
D
D
S
F
S
E
P
R
I
A
E
L
Cat
Felis silvestris
Mouse
Mus musculus
P70303
586
65496
P576
D
A
S
D
D
S
F
P
E
A
K
L
A
E
L
Rat
Rattus norvegicus
Q5U2N0
586
65655
S576
D
A
S
D
D
S
F
S
E
A
K
F
A
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515783
691
77183
T576
L
S
A
Y
G
Y
G
T
Q
Q
L
A
G
D
T
Chicken
Gallus gallus
Q5F3Z1
586
66050
P576
D
L
S
D
D
S
S
P
E
K
E
F
P
K
S
Frog
Xenopus laevis
Q6GME1
578
65100
N565
G
C
K
L
S
P
R
N
S
Y
S
E
H
S
D
Zebra Danio
Brachydanio rerio
Q6PEI7
591
66577
P576
D
R
S
G
S
S
S
P
D
L
E
I
A
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUL1
627
69429
S576
A
S
S
D
E
E
D
S
V
V
G
L
A
G
A
Honey Bee
Apis mellifera
XP_624223
604
67926
L577
N
E
S
D
N
E
C
L
V
D
S
I
A
K
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P28274
579
64692
Y568
Q
D
V
I
E
G
K
Y
D
L
E
A
G
E
N
Red Bread Mold
Neurospora crassa
Q7RZV2
568
63157
A559
I
L
Q
D
A
G
F
A
N
G
S
I
N
G
A
Conservation
Percent
Protein Identity:
100
92.8
88.1
96.2
N.A.
90.4
90.6
N.A.
75.5
85.4
79.8
75.6
N.A.
61
63
N.A.
N.A.
Protein Similarity:
100
94.5
89.7
97.9
N.A.
95
94.7
N.A.
78.7
91.3
89
85.2
N.A.
74
77.3
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
73.3
80
N.A.
0
40
0
40
N.A.
26.6
26.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
33.3
46.6
6.6
53.3
N.A.
46.6
46.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
54.2
52
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
71.5
68.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
43
8
0
8
0
0
8
0
15
0
15
65
0
15
% A
% Cys:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
58
8
0
72
50
0
8
0
15
8
0
0
0
15
8
% D
% Glu:
0
8
0
0
15
15
0
0
50
0
22
8
0
50
0
% E
% Phe:
0
0
0
0
0
0
50
0
0
0
0
15
0
0
0
% F
% Gly:
8
0
0
8
8
15
8
0
0
8
8
0
15
15
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
8
0
0
8
0
0
0
0
0
0
0
50
0
0
0
% I
% Lys:
0
0
8
0
0
0
8
0
0
8
15
0
0
15
0
% K
% Leu:
8
15
0
8
0
0
0
8
0
15
8
15
0
0
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
0
0
8
8
0
0
0
8
0
8
% N
% Pro:
0
0
0
0
0
8
0
22
0
29
0
0
8
0
0
% P
% Gln:
8
0
8
0
0
0
0
0
8
8
0
0
0
0
8
% Q
% Arg:
0
8
0
0
0
0
8
0
0
0
29
0
0
0
0
% R
% Ser:
0
15
72
0
15
58
15
43
8
0
22
0
0
8
8
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% T
% Val:
0
0
8
0
0
0
0
0
15
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
8
0
8
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _