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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTPS2
All Species:
45.76
Human Site:
S421
Identified Species:
77.44
UniProt:
Q9NRF8
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRF8
NP_001137474.1
586
65678
S421
L
N
L
K
D
A
D
S
T
E
F
R
P
N
A
Chimpanzee
Pan troglodytes
XP_520953
586
65363
S421
L
N
L
K
D
A
D
S
T
E
F
R
P
N
A
Rhesus Macaque
Macaca mulatta
XP_001117012
616
69695
S451
L
N
L
K
D
A
D
S
T
E
F
R
P
N
A
Dog
Lupus familis
XP_537968
586
65447
S421
L
N
L
K
D
A
D
S
T
E
F
E
P
N
A
Cat
Felis silvestris
Mouse
Mus musculus
P70303
586
65496
S421
L
N
L
K
D
A
N
S
T
E
F
E
P
N
T
Rat
Rattus norvegicus
Q5U2N0
586
65655
S421
L
N
L
K
D
A
N
S
T
E
F
D
P
N
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515783
691
77183
S421
L
G
W
K
D
A
D
S
T
E
F
E
P
Q
T
Chicken
Gallus gallus
Q5F3Z1
586
66050
S421
L
N
W
K
D
A
N
S
T
E
F
D
P
D
T
Frog
Xenopus laevis
Q6GME1
578
65100
S421
L
K
M
T
D
A
N
S
T
E
F
D
P
N
T
Zebra Danio
Brachydanio rerio
Q6PEI7
591
66577
S421
L
D
W
T
D
A
N
S
T
E
F
D
P
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUL1
627
69429
T421
L
G
L
K
D
A
N
T
T
E
I
D
P
N
T
Honey Bee
Apis mellifera
XP_624223
604
67926
S422
L
N
I
E
S
A
N
S
M
E
I
D
P
E
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P28274
579
64692
S426
L
G
R
K
D
S
H
S
A
E
F
Y
P
D
I
Red Bread Mold
Neurospora crassa
Q7RZV2
568
63157
S413
C
E
L
K
D
A
T
S
E
E
F
D
A
N
A
Conservation
Percent
Protein Identity:
100
92.8
88.1
96.2
N.A.
90.4
90.6
N.A.
75.5
85.4
79.8
75.6
N.A.
61
63
N.A.
N.A.
Protein Similarity:
100
94.5
89.7
97.9
N.A.
95
94.7
N.A.
78.7
91.3
89
85.2
N.A.
74
77.3
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
80
80
N.A.
66.6
66.6
60
53.3
N.A.
60
40
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
66.6
80
73.3
66.6
N.A.
73.3
60
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
54.2
52
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
71.5
68.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
60
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
93
0
0
8
0
0
0
8
0
36
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
93
0
36
0
0
0
0
50
0
15
0
% D
% Glu:
0
8
0
8
0
0
0
0
8
100
0
22
0
15
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
86
0
0
0
0
% F
% Gly:
0
22
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
15
0
0
0
8
% I
% Lys:
0
8
0
79
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
93
0
58
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
58
0
0
0
0
50
0
0
0
0
0
0
65
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
93
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
22
0
0
0
% R
% Ser:
0
0
0
0
8
8
0
93
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
15
0
0
8
8
79
0
0
0
0
0
58
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
22
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _