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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF4ENIF1
All Species:
25.76
Human Site:
S741
Identified Species:
51.52
UniProt:
Q9NRA8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRA8
NP_001157973.1
985
108201
S741
S
E
E
N
L
L
S
S
S
S
V
P
S
A
D
Chimpanzee
Pan troglodytes
XP_001149434
985
108212
S741
S
E
E
N
L
L
S
S
S
S
V
P
S
A
D
Rhesus Macaque
Macaca mulatta
XP_001111584
982
107599
S738
S
E
E
N
L
L
S
S
S
S
V
P
S
A
D
Dog
Lupus familis
XP_543492
986
108377
S742
S
E
E
N
L
L
S
S
N
S
V
P
S
A
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9EST3
983
107966
S740
S
E
E
N
L
L
S
S
N
P
I
P
N
T
D
Rat
Rattus norvegicus
NP_001100700
985
108290
S741
S
E
E
N
L
L
S
S
N
S
I
S
N
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506005
628
67762
L414
R
S
A
C
S
T
P
L
S
Q
T
N
R
Y
T
Chicken
Gallus gallus
XP_415254
1367
148531
S1125
N
E
D
N
L
L
S
S
S
V
E
N
A
D
Q
Frog
Xenopus laevis
NP_001086710
771
85462
D557
I
M
Q
D
S
P
Q
D
T
S
L
V
M
G
N
Zebra Danio
Brachydanio rerio
NP_001013556
747
83379
G533
D
T
S
G
P
Q
T
G
G
V
K
A
C
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122940
1223
137663
L984
Q
M
Q
S
A
V
Q
L
L
T
Q
G
V
L
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781676
1583
172338
T1135
S
S
G
T
P
P
G
T
P
G
H
R
T
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
93
95.8
N.A.
89.9
90.7
N.A.
53.4
59.9
54.2
44
N.A.
N.A.
23.2
N.A.
22.5
Protein Similarity:
100
99.9
95.8
97.8
N.A.
94.8
95.1
N.A.
58
66.1
64.5
55.9
N.A.
N.A.
39.6
N.A.
36.3
P-Site Identity:
100
100
100
93.3
N.A.
66.6
66.6
N.A.
6.6
46.6
6.6
0
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
86.6
93.3
N.A.
6.6
66.6
40
13.3
N.A.
N.A.
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
0
0
0
0
0
0
9
9
34
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
9
0
9
9
0
0
0
9
0
0
0
0
0
9
50
% D
% Glu:
0
59
50
0
0
0
0
0
0
0
9
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
9
0
0
9
9
9
9
0
9
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% K
% Leu:
0
0
0
0
59
59
0
17
9
0
9
0
0
9
0
% L
% Met:
0
17
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
9
0
0
59
0
0
0
0
25
0
0
17
17
0
9
% N
% Pro:
0
0
0
0
17
17
9
0
9
9
0
42
0
9
0
% P
% Gln:
9
0
17
0
0
9
17
0
0
9
9
0
0
0
9
% Q
% Arg:
9
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% R
% Ser:
59
17
9
9
17
0
59
59
42
50
0
9
34
17
17
% S
% Thr:
0
9
0
9
0
9
9
9
9
9
9
0
9
9
17
% T
% Val:
0
0
0
0
0
9
0
0
0
17
34
9
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _