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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF4ENIF1
All Species:
27.88
Human Site:
S712
Identified Species:
55.76
UniProt:
Q9NRA8
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRA8
NP_001157973.1
985
108201
S712
M
Y
E
S
K
E
K
S
K
E
E
P
A
S
G
Chimpanzee
Pan troglodytes
XP_001149434
985
108212
S712
M
Y
E
S
K
E
K
S
K
E
E
P
A
S
G
Rhesus Macaque
Macaca mulatta
XP_001111584
982
107599
S709
M
Y
E
S
K
E
K
S
K
E
E
P
I
S
G
Dog
Lupus familis
XP_543492
986
108377
S713
M
Y
E
S
K
E
K
S
K
E
E
P
A
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9EST3
983
107966
T711
M
Y
E
S
R
E
K
T
K
E
E
M
A
P
G
Rat
Rattus norvegicus
NP_001100700
985
108290
S712
M
Y
E
S
R
E
K
S
K
E
E
I
A
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506005
628
67762
S385
E
D
H
L
L
S
S
S
S
V
V
N
S
D
Q
Chicken
Gallus gallus
XP_415254
1367
148531
S1096
M
Y
E
S
K
E
K
S
K
E
E
P
V
S
G
Frog
Xenopus laevis
NP_001086710
771
85462
K528
I
K
D
E
P
T
E
K
Q
N
V
S
G
K
E
Zebra Danio
Brachydanio rerio
NP_001013556
747
83379
T504
R
P
G
S
K
E
E
T
V
N
S
H
N
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122940
1223
137663
E955
R
K
M
T
A
D
K
E
P
E
G
N
S
N
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781676
1583
172338
P1106
Q
Q
Q
Q
Q
Q
H
P
G
Q
Q
A
N
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
93
95.8
N.A.
89.9
90.7
N.A.
53.4
59.9
54.2
44
N.A.
N.A.
23.2
N.A.
22.5
Protein Similarity:
100
99.9
95.8
97.8
N.A.
94.8
95.1
N.A.
58
66.1
64.5
55.9
N.A.
N.A.
39.6
N.A.
36.3
P-Site Identity:
100
100
93.3
100
N.A.
73.3
80
N.A.
6.6
93.3
0
26.6
N.A.
N.A.
13.3
N.A.
0
P-Site Similarity:
100
100
93.3
100
N.A.
86.6
86.6
N.A.
13.3
93.3
26.6
40
N.A.
N.A.
40
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
0
0
0
9
42
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
0
0
9
0
0
0
0
0
0
0
9
9
% D
% Glu:
9
0
59
9
0
67
17
9
0
67
59
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
9
0
9
0
9
0
59
% G
% His:
0
0
9
0
0
0
9
0
0
0
0
9
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% I
% Lys:
0
17
0
0
50
0
67
9
59
0
0
0
0
9
0
% K
% Leu:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% L
% Met:
59
0
9
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
17
0
17
17
9
0
% N
% Pro:
0
9
0
0
9
0
0
9
9
0
0
42
0
17
0
% P
% Gln:
9
9
9
9
9
9
0
0
9
9
9
0
0
9
25
% Q
% Arg:
17
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
67
0
9
9
59
9
0
9
9
17
50
0
% S
% Thr:
0
0
0
9
0
9
0
17
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
9
9
17
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
59
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _