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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF4ENIF1
All Species:
22.12
Human Site:
S259
Identified Species:
44.24
UniProt:
Q9NRA8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRA8
NP_001157973.1
985
108201
S259
R
T
R
R
R
T
A
S
V
K
E
G
I
V
E
Chimpanzee
Pan troglodytes
XP_001149434
985
108212
S259
R
T
R
R
R
T
A
S
V
K
E
G
I
V
E
Rhesus Macaque
Macaca mulatta
XP_001111584
982
107599
E256
K
K
K
K
P
S
L
E
K
E
L
G
I
V
E
Dog
Lupus familis
XP_543492
986
108377
S259
R
T
R
R
R
T
A
S
V
K
E
G
I
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9EST3
983
107966
S258
R
T
R
R
R
T
A
S
V
K
E
G
I
V
E
Rat
Rattus norvegicus
NP_001100700
985
108290
S259
R
T
R
R
R
T
A
S
V
R
E
G
I
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506005
628
67762
A15
A
I
S
G
L
E
Q
A
I
L
S
P
G
Q
N
Chicken
Gallus gallus
XP_415254
1367
148531
S644
R
T
R
R
R
T
A
S
L
K
E
G
I
E
C
Frog
Xenopus laevis
NP_001086710
771
85462
R158
S
R
R
I
G
S
G
R
L
M
T
A
R
G
F
Zebra Danio
Brachydanio rerio
NP_001013556
747
83379
P134
L
P
R
R
P
T
S
P
L
E
N
K
E
N
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122940
1223
137663
R353
Q
T
P
V
Q
K
K
R
G
K
K
N
S
L
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781676
1583
172338
A316
K
G
R
R
P
S
V
A
D
R
N
G
S
M
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
93
95.8
N.A.
89.9
90.7
N.A.
53.4
59.9
54.2
44
N.A.
N.A.
23.2
N.A.
22.5
Protein Similarity:
100
99.9
95.8
97.8
N.A.
94.8
95.1
N.A.
58
66.1
64.5
55.9
N.A.
N.A.
39.6
N.A.
36.3
P-Site Identity:
100
100
26.6
100
N.A.
100
93.3
N.A.
0
80
6.6
26.6
N.A.
N.A.
20
N.A.
26.6
P-Site Similarity:
100
100
60
100
N.A.
100
100
N.A.
13.3
86.6
20
46.6
N.A.
N.A.
46.6
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
50
17
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
9
0
9
0
17
50
0
9
9
75
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
9
0
9
9
0
9
0
9
0
0
67
9
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
9
0
0
0
0
9
0
0
0
59
0
0
% I
% Lys:
17
9
9
9
0
9
9
0
9
50
9
9
0
0
0
% K
% Leu:
9
0
0
0
9
0
9
0
25
9
9
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
17
9
0
9
9
% N
% Pro:
0
9
9
0
25
0
0
9
0
0
0
9
0
0
0
% P
% Gln:
9
0
0
0
9
0
9
0
0
0
0
0
0
9
0
% Q
% Arg:
50
9
75
67
50
0
0
17
0
17
0
0
9
0
0
% R
% Ser:
9
0
9
0
0
25
9
50
0
0
9
0
17
0
0
% S
% Thr:
0
59
0
0
0
59
0
0
0
0
9
0
0
0
0
% T
% Val:
0
0
0
9
0
0
9
0
42
0
0
0
0
50
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _