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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPHK2
All Species:
17.88
Human Site:
Y628
Identified Species:
39.33
UniProt:
Q9NRA0
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRA0
NP_064511.2
654
69217
Y628
V
D
G
E
Q
V
E
Y
G
P
L
Q
A
Q
M
Chimpanzee
Pan troglodytes
XP_001171276
652
69465
Y626
V
D
G
E
Q
V
E
Y
G
P
L
Q
A
Q
M
Rhesus Macaque
Macaca mulatta
XP_001113908
653
69532
Y627
V
D
G
E
Q
V
E
Y
G
P
L
Q
A
Q
M
Dog
Lupus familis
XP_541516
663
70246
Y637
V
D
G
E
Q
V
E
Y
G
P
L
Q
A
Q
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIA7
617
65600
Y592
V
D
G
E
L
V
E
Y
G
P
I
Q
A
Q
V
Rat
Rattus norvegicus
Q91V26
383
42400
M360
V
H
P
N
Y
L
W
M
V
S
G
S
S
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088560
509
55981
I486
M
T
V
D
G
E
A
I
P
C
C
S
L
Q
G
Zebra Danio
Brachydanio rerio
Q7ZW00
422
47526
V399
Y
E
A
M
S
V
E
V
R
L
L
P
R
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647762
661
73852
V636
D
N
H
G
I
I
T
V
D
G
E
R
V
E
F
Honey Bee
Apis mellifera
XP_394823
620
69588
I594
E
E
G
V
N
G
Y
I
T
V
D
G
E
R
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LRB0
763
83573
H740
D
G
E
L
F
A
L
H
G
E
V
I
S
T
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96
96.6
90.8
N.A.
78.4
26.6
N.A.
N.A.
N.A.
32.8
20.4
N.A.
32.2
29.3
N.A.
N.A.
Protein Similarity:
100
96.6
97.4
92.9
N.A.
84.2
37.9
N.A.
N.A.
N.A.
46.6
34
N.A.
46.4
45.7
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
80
6.6
N.A.
N.A.
N.A.
6.6
20
N.A.
0
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
20
N.A.
N.A.
N.A.
20
40
N.A.
26.6
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
10
10
0
0
0
0
0
46
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% C
% Asp:
19
46
0
10
0
0
0
0
10
0
10
0
0
10
0
% D
% Glu:
10
19
10
46
0
10
55
0
0
10
10
0
10
10
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
10
55
10
10
10
0
0
55
10
10
10
0
0
10
% G
% His:
0
10
10
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
10
0
19
0
0
10
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
0
0
10
10
10
10
0
0
10
46
0
10
0
10
% L
% Met:
10
0
0
10
0
0
0
10
0
0
0
0
0
0
46
% M
% Asn:
0
10
0
10
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
10
46
0
10
0
0
0
% P
% Gln:
0
0
0
0
37
0
0
0
0
0
0
46
0
55
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
10
10
10
0
% R
% Ser:
0
0
0
0
10
0
0
0
0
10
0
19
19
0
10
% S
% Thr:
0
10
0
0
0
0
10
0
10
0
0
0
0
10
0
% T
% Val:
55
0
10
10
0
55
0
19
10
10
10
0
10
0
19
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
10
0
10
46
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _