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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ASAH2
All Species:
14.85
Human Site:
S126
Identified Species:
29.7
UniProt:
Q9NR71
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NR71
NP_001072984.1
780
85516
S126
N
L
M
G
Y
G
K
S
G
Q
N
A
Q
G
I
Chimpanzee
Pan troglodytes
XP_507791
780
85671
S126
N
L
M
G
Y
G
K
S
S
Q
N
A
Q
G
I
Rhesus Macaque
Macaca mulatta
XP_001100613
780
85507
S126
N
L
M
G
Y
S
K
S
G
Q
N
A
Q
G
I
Dog
Lupus familis
XP_861054
780
85672
T126
N
L
M
G
Y
S
K
T
G
Q
N
A
R
G
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHE3
756
83491
S126
I
L
A
D
P
D
G
S
N
R
M
A
F
V
S
Rat
Rattus norvegicus
Q91XT9
761
83469
A126
F
S
R
A
F
I
L
A
D
P
D
G
S
N
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506611
746
81905
T116
L
I
A
E
A
N
T
T
K
R
V
V
F
V
S
Chicken
Gallus gallus
XP_421560
811
88602
P160
P
L
M
G
Y
A
N
P
D
Q
V
G
G
G
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5W7F1
743
82050
F112
D
G
N
K
R
V
V
F
V
T
S
D
I
G
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA70
704
78213
R74
V
E
D
E
K
G
N
R
V
A
F
V
S
A
D
Honey Bee
Apis mellifera
XP_393129
717
79852
M87
F
V
S
V
D
S
A
M
I
G
N
G
I
R
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q304B9
757
83246
L126
H
A
G
P
G
G
Y
L
Q
Y
V
T
Y
I
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.2
84.8
N.A.
79.2
79.4
N.A.
73.5
62.6
N.A.
57.3
N.A.
40.9
41
N.A.
N.A.
Protein Similarity:
100
99.3
97.8
91.7
N.A.
88
89.2
N.A.
83.7
73.2
N.A.
70.6
N.A.
57.1
57.3
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
80
N.A.
20
0
N.A.
0
40
N.A.
6.6
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
26.6
20
N.A.
20
46.6
N.A.
26.6
N.A.
6.6
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
17
9
9
9
9
9
0
9
0
42
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
9
9
9
0
0
17
0
9
9
0
0
9
% D
% Glu:
0
9
0
17
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
17
0
0
0
9
0
0
9
0
0
9
0
17
0
0
% F
% Gly:
0
9
9
42
9
34
9
0
25
9
0
25
9
50
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
9
0
0
0
9
0
0
9
0
0
0
17
9
34
% I
% Lys:
0
0
0
9
9
0
34
0
9
0
0
0
0
0
0
% K
% Leu:
9
50
0
0
0
0
9
9
0
0
0
0
0
0
9
% L
% Met:
0
0
42
0
0
0
0
9
0
0
9
0
0
0
9
% M
% Asn:
34
0
9
0
0
9
17
0
9
0
42
0
0
9
0
% N
% Pro:
9
0
0
9
9
0
0
9
0
9
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
9
42
0
0
25
0
9
% Q
% Arg:
0
0
9
0
9
0
0
9
0
17
0
0
9
9
9
% R
% Ser:
0
9
9
0
0
25
0
34
9
0
9
0
17
0
17
% S
% Thr:
0
0
0
0
0
0
9
17
0
9
0
9
0
0
0
% T
% Val:
9
9
0
9
0
9
9
0
17
0
25
17
0
17
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
42
0
9
0
0
9
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _