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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NANS
All Species:
29.39
Human Site:
S275
Identified Species:
58.79
UniProt:
Q9NR45
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NR45
NP_061819.2
359
40308
S275
L
V
E
R
A
L
G
S
P
T
K
Q
L
L
P
Chimpanzee
Pan troglodytes
XP_001157766
320
35890
R237
L
G
A
K
V
L
E
R
H
I
T
L
D
K
T
Rhesus Macaque
Macaca mulatta
XP_001113519
274
30677
Q194
A
L
G
S
P
T
K
Q
L
L
P
C
E
M
A
Dog
Lupus familis
XP_538746
359
40228
S275
L
V
E
R
A
M
G
S
P
T
K
Q
L
L
P
Cat
Felis silvestris
Mouse
Mus musculus
NP_444409
359
40006
S275
L
V
E
R
A
L
G
S
P
T
K
Q
L
L
P
Rat
Rattus norvegicus
NP_001100125
359
40033
S275
L
V
E
R
A
L
G
S
P
A
K
Q
L
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506765
359
40209
S275
L
V
E
K
A
M
G
S
P
I
K
Q
L
L
P
Chicken
Gallus gallus
NP_001007976
359
40126
S275
A
V
E
K
A
M
G
S
P
I
K
Q
L
L
P
Frog
Xenopus laevis
NP_001087593
359
40302
S275
L
V
E
K
A
M
G
S
S
V
K
R
L
L
P
Zebra Danio
Brachydanio rerio
NP_996660
359
40126
T275
I
V
E
R
A
L
G
T
G
L
K
R
M
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650195
372
41200
P272
N
F
K
L
S
S
V
P
M
P
P
Q
E
I
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783181
296
33461
G216
D
I
P
I
G
Y
S
G
H
E
G
G
L
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.5
75.7
95.8
N.A.
94.7
94.9
N.A.
88.3
86.9
77.4
78.8
N.A.
47.5
N.A.
N.A.
59.3
Protein Similarity:
100
85.7
76
98.8
N.A.
97.7
97.4
N.A.
94.9
94.1
90.8
92.1
N.A.
65.3
N.A.
N.A.
71.5
P-Site Identity:
100
13.3
0
93.3
N.A.
100
93.3
N.A.
80
73.3
66.6
60
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
20
13.3
100
N.A.
100
93.3
N.A.
93.3
86.6
86.6
86.6
N.A.
26.6
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
9
0
67
0
0
0
0
9
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% D
% Glu:
0
0
67
0
0
0
9
0
0
9
0
0
17
0
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
9
0
9
0
67
9
9
0
9
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% H
% Ile:
9
9
0
9
0
0
0
0
0
25
0
0
0
9
9
% I
% Lys:
0
0
9
34
0
0
9
0
0
0
67
0
0
9
0
% K
% Leu:
59
9
0
9
0
42
0
0
9
17
0
9
67
67
0
% L
% Met:
0
0
0
0
0
34
0
0
9
0
0
0
9
9
0
% M
% Asn:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
9
0
9
0
0
9
50
9
17
0
0
0
67
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
0
59
0
0
0
% Q
% Arg:
0
0
0
42
0
0
0
9
0
0
0
17
0
0
0
% R
% Ser:
0
0
0
9
9
9
9
59
9
0
0
0
0
9
0
% S
% Thr:
0
0
0
0
0
9
0
9
0
25
9
0
0
0
9
% T
% Val:
0
67
0
0
9
0
9
0
0
9
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _