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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX21
All Species:
30.3
Human Site:
S277
Identified Species:
51.28
UniProt:
Q9NR30
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NR30
NP_004719.2
783
87344
S277
R
E
L
A
N
Q
V
S
K
D
F
S
D
I
T
Chimpanzee
Pan troglodytes
XP_507825
783
87227
S277
R
E
L
A
N
Q
V
S
K
D
F
S
D
I
T
Rhesus Macaque
Macaca mulatta
XP_001110939
783
87067
S277
R
E
L
A
N
Q
V
S
K
D
F
S
D
I
T
Dog
Lupus familis
XP_851746
784
87489
S278
R
E
L
A
N
Q
V
S
R
D
F
S
D
I
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIK5
851
93564
S349
R
E
L
A
N
Q
V
S
K
D
F
S
D
I
T
Rat
Rattus norvegicus
Q3B8Q1
782
85947
S273
R
E
L
A
N
Q
V
S
K
D
F
S
D
I
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519340
757
84164
G263
R
E
L
A
I
Q
V
G
R
D
F
S
D
I
T
Chicken
Gallus gallus
XP_001232052
713
79167
Q248
G
G
T
P
Y
N
G
Q
I
D
L
I
R
S
G
Frog
Xenopus laevis
NP_001082033
800
89347
T312
R
E
L
A
I
Q
I
T
N
E
L
R
S
M
T
Zebra Danio
Brachydanio rerio
NP_001120807
759
84566
T257
R
E
L
A
I
Q
V
T
K
D
F
K
D
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786504
657
72975
E192
E
L
A
K
Q
I
S
E
Y
F
E
A
I
G
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39189
671
72872
C206
G
S
L
G
L
S
S
C
C
L
Y
G
G
D
S
Baker's Yeast
Sacchar. cerevisiae
P24784
617
67899
P152
S
G
K
D
V
P
E
P
I
L
D
F
S
S
P
Red Bread Mold
Neurospora crassa
Q9P6U9
688
72037
Y223
V
P
T
P
V
Q
K
Y
S
I
P
I
V
M
G
Conservation
Percent
Protein Identity:
100
99.8
97.6
87.2
N.A.
76.1
84.9
N.A.
66.4
62.2
51.7
62.2
N.A.
N.A.
N.A.
N.A.
45.5
Protein Similarity:
100
99.8
98.8
91.5
N.A.
82.4
90.2
N.A.
78.4
75.8
69.6
75.6
N.A.
N.A.
N.A.
N.A.
60.5
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
80
6.6
40
80
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
6.6
66.6
86.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
38
23.8
26.4
Protein Similarity:
N.A.
N.A.
N.A.
53.3
40.2
39.8
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
0
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
65
0
0
0
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
65
8
0
58
8
0
% D
% Glu:
8
65
0
0
0
0
8
8
0
8
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
58
8
0
0
0
% F
% Gly:
15
15
0
8
0
0
8
8
0
0
0
8
8
8
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
22
8
8
0
15
8
0
15
8
58
0
% I
% Lys:
0
0
8
8
0
0
8
0
43
0
0
8
0
0
0
% K
% Leu:
0
8
72
0
8
0
0
0
0
15
15
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% M
% Asn:
0
0
0
0
43
8
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
8
0
15
0
8
0
8
0
0
8
0
0
0
15
% P
% Gln:
0
0
0
0
8
72
0
8
0
0
0
0
0
0
0
% Q
% Arg:
65
0
0
0
0
0
0
0
15
0
0
8
8
0
0
% R
% Ser:
8
8
0
0
0
8
15
43
8
0
0
50
15
15
8
% S
% Thr:
0
0
15
0
0
0
0
15
0
0
0
0
0
0
65
% T
% Val:
8
0
0
0
15
0
58
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
8
8
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _