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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX21
All Species:
26.67
Human Site:
S222
Identified Species:
45.13
UniProt:
Q9NR30
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NR30
NP_004719.2
783
87344
S222
K
T
F
H
H
V
Y
S
G
K
D
L
I
A
Q
Chimpanzee
Pan troglodytes
XP_507825
783
87227
S222
K
T
F
H
H
V
Y
S
G
K
D
L
I
A
Q
Rhesus Macaque
Macaca mulatta
XP_001110939
783
87067
S222
K
T
F
H
H
V
Y
S
G
K
D
L
I
A
Q
Dog
Lupus familis
XP_851746
784
87489
S223
K
T
F
Y
H
V
Y
S
G
K
D
L
I
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIK5
851
93564
S294
K
T
F
H
H
V
Y
S
G
K
D
L
I
A
Q
Rat
Rattus norvegicus
Q3B8Q1
782
85947
S218
K
T
F
H
H
V
Y
S
G
K
D
L
I
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519340
757
84164
K222
Q
A
R
T
G
T
G
K
T
F
S
F
A
I
P
Chicken
Gallus gallus
XP_001232052
713
79167
P208
E
R
R
R
G
R
S
P
K
V
L
V
L
A
P
Frog
Xenopus laevis
NP_001082033
800
89347
S257
K
T
F
H
T
V
Y
S
G
K
D
V
V
V
Q
Zebra Danio
Brachydanio rerio
NP_001120807
759
84566
K216
Q
A
R
T
G
T
G
K
T
F
S
F
A
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786504
657
72975
K152
Q
A
R
T
G
T
G
K
T
L
S
F
V
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39189
671
72872
K166
V
N
G
P
A
K
S
K
R
K
M
G
Y
G
R
Baker's Yeast
Sacchar. cerevisiae
P24784
617
67899
A112
H
I
P
G
P
K
N
A
K
L
E
A
E
L
F
Red Bread Mold
Neurospora crassa
Q9P6U9
688
72037
E183
K
Y
D
D
I
P
V
E
A
S
G
D
N
V
P
Conservation
Percent
Protein Identity:
100
99.8
97.6
87.2
N.A.
76.1
84.9
N.A.
66.4
62.2
51.7
62.2
N.A.
N.A.
N.A.
N.A.
45.5
Protein Similarity:
100
99.8
98.8
91.5
N.A.
82.4
90.2
N.A.
78.4
75.8
69.6
75.6
N.A.
N.A.
N.A.
N.A.
60.5
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
0
6.6
73.3
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
6.6
26.6
86.6
6.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
38
23.8
26.4
Protein Similarity:
N.A.
N.A.
N.A.
53.3
40.2
39.8
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
22
0
0
8
0
0
8
8
0
0
8
15
50
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
0
0
0
0
0
50
8
0
0
0
% D
% Glu:
8
0
0
0
0
0
0
8
0
0
8
0
8
0
0
% E
% Phe:
0
0
50
0
0
0
0
0
0
15
0
22
0
0
8
% F
% Gly:
0
0
8
8
29
0
22
0
50
0
8
8
0
8
0
% G
% His:
8
0
0
43
43
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
8
0
0
0
0
0
0
0
43
8
0
% I
% Lys:
58
0
0
0
0
15
0
29
15
58
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
15
8
43
8
15
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
8
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
8
8
8
8
0
8
0
0
0
0
0
0
36
% P
% Gln:
22
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% Q
% Arg:
0
8
29
8
0
8
0
0
8
0
0
0
0
0
8
% R
% Ser:
0
0
0
0
0
0
15
50
0
8
22
0
0
0
0
% S
% Thr:
0
50
0
22
8
22
0
0
22
0
0
0
0
0
0
% T
% Val:
8
0
0
0
0
50
8
0
0
8
0
15
15
22
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
8
0
0
50
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _