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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK6
All Species:
36.97
Human Site:
T535
Identified Species:
58.1
UniProt:
Q9NQU5
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQU5
NP_001122100.1
681
74869
T535
K
S
D
S
I
L
L
T
L
D
G
R
V
K
L
Chimpanzee
Pan troglodytes
XP_510301
627
67581
V487
A
Y
L
H
A
Q
G
V
I
H
R
D
I
K
S
Rhesus Macaque
Macaca mulatta
XP_001093484
681
74821
T535
K
S
D
S
I
L
L
T
L
D
G
R
V
K
L
Dog
Lupus familis
XP_544614
968
105825
T822
K
S
D
S
I
L
L
T
L
D
G
R
V
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3ULB5
682
74848
T536
K
S
D
S
I
L
L
T
L
D
G
R
V
K
L
Rat
Rattus norvegicus
Q62829
544
60692
T404
M
D
G
S
V
K
L
T
D
F
G
F
C
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515215
639
68748
G499
R
V
K
L
S
D
F
G
F
C
A
Q
I
S
K
Chicken
Gallus gallus
XP_426393
667
74767
T521
K
S
D
S
I
L
L
T
L
D
G
R
V
K
L
Frog
Xenopus laevis
NP_001082100
650
73749
T508
K
S
D
S
I
L
L
T
H
D
G
R
V
K
L
Zebra Danio
Brachydanio rerio
XP_001919719
693
77347
S547
K
S
D
S
I
L
L
S
L
D
G
R
I
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
G499
S
I
L
L
A
A
D
G
R
V
K
L
S
D
F
Honey Bee
Apis mellifera
XP_001122147
624
70155
R484
I
L
L
T
A
D
G
R
V
K
L
S
D
F
G
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
D432
D
G
S
V
K
L
T
D
F
G
F
C
A
Q
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
S748
K
S
D
N
I
L
L
S
M
E
G
D
I
K
L
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
S802
K
S
D
N
I
L
L
S
M
E
G
N
I
K
L
Conservation
Percent
Protein Identity:
100
52.7
98.5
66.4
N.A.
92.5
30.6
N.A.
62.2
75.9
46.7
52.5
N.A.
44.3
44.9
29.8
N.A.
Protein Similarity:
100
60.7
98.9
67.6
N.A.
95.5
48.4
N.A.
69.9
82.3
61.6
64.5
N.A.
57.5
57.5
47.2
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
100
26.6
N.A.
0
100
93.3
86.6
N.A.
0
0
13.3
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
33.3
N.A.
20
100
93.3
100
N.A.
0
13.3
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
28
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
41.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
60
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
93.3
93.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
20
7
0
0
0
0
7
0
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
7
7
0
0
% C
% Asp:
7
7
60
0
0
14
7
7
7
47
0
14
7
7
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
14
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
7
0
14
7
7
7
0
7
7
% F
% Gly:
0
7
7
0
0
0
14
14
0
7
67
0
0
0
7
% G
% His:
0
0
0
7
0
0
0
0
7
7
0
0
0
0
0
% H
% Ile:
7
7
0
0
60
0
0
0
7
0
0
0
34
0
0
% I
% Lys:
60
0
7
0
7
7
0
0
0
7
7
0
0
67
7
% K
% Leu:
0
7
20
14
0
67
67
0
40
0
7
7
0
0
67
% L
% Met:
7
0
0
0
0
0
0
0
14
0
0
0
0
0
0
% M
% Asn:
0
0
0
14
0
0
0
0
0
0
0
7
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
7
0
0
0
0
0
7
0
7
7
% Q
% Arg:
7
0
0
0
0
0
0
7
7
0
7
47
0
0
0
% R
% Ser:
7
60
7
54
7
0
0
20
0
0
0
7
7
7
7
% S
% Thr:
0
0
0
7
0
0
7
47
0
0
0
0
0
0
0
% T
% Val:
0
7
0
7
7
0
0
7
7
7
0
0
40
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _