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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK6 All Species: 14.24
Human Site: T238 Identified Species: 22.38
UniProt: Q9NQU5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQU5 NP_001122100.1 681 74869 T238 S C L V G S A T G R P G G E G
Chimpanzee Pan troglodytes XP_510301 627 67581 P217 P P Q K D N P P S L V A K A Q
Rhesus Macaque Macaca mulatta XP_001093484 681 74821 T238 S C L V G S A T G R P G G E G
Dog Lupus familis XP_544614 968 105825 T525 S C L V G S A T G R P G G E G
Cat Felis silvestris
Mouse Mus musculus Q3ULB5 682 74848 I239 S C L V G S A I G R P G G E G
Rat Rattus norvegicus Q62829 544 60692 N134 D S K E T V N N Q K Y M S F T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515215 639 68748 P229 R P G R E G S P S S Q A R D S
Chicken Gallus gallus XP_426393 667 74767 G238 N S R P S G E G S P S S K S R
Frog Xenopus laevis NP_001082100 650 73749 S233 A Y T S G E G S P Q S P R D K
Zebra Danio Brachydanio rerio XP_001919719 693 77347 H238 E F P I I F T H N P R P I T C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXE5 639 69601 S229 R S N L A P P S G G S M P Q Q
Honey Bee Apis mellifera XP_001122147 624 70155 S214 S L N F Q N L S P I N T P Q C
Nematode Worm Caenorhab. elegans Q17850 572 63863 S162 P Q P Y S T S S L P Y H G N K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03497 939 102344 I389 N M Q A V M D I V K F Y Q D V
Red Bread Mold Neurospora crassa Q7RZD3 954 103773 L387 P Q I L V D V L T F Y K E T T
Conservation
Percent
Protein Identity: 100 52.7 98.5 66.4 N.A. 92.5 30.6 N.A. 62.2 75.9 46.7 52.5 N.A. 44.3 44.9 29.8 N.A.
Protein Similarity: 100 60.7 98.9 67.6 N.A. 95.5 48.4 N.A. 69.9 82.3 61.6 64.5 N.A. 57.5 57.5 47.2 N.A.
P-Site Identity: 100 0 100 100 N.A. 93.3 0 N.A. 0 0 6.6 0 N.A. 6.6 6.6 6.6 N.A.
P-Site Similarity: 100 6.6 100 100 N.A. 93.3 6.6 N.A. 13.3 6.6 33.3 6.6 N.A. 26.6 26.6 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.5 28
Protein Similarity: N.A. N.A. N.A. N.A. 43.1 41.6
P-Site Identity: N.A. N.A. N.A. N.A. 0 0
P-Site Similarity: N.A. N.A. N.A. N.A. 20 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 7 7 0 27 0 0 0 0 14 0 7 0 % A
% Cys: 0 27 0 0 0 0 0 0 0 0 0 0 0 0 14 % C
% Asp: 7 0 0 0 7 7 7 0 0 0 0 0 0 20 0 % D
% Glu: 7 0 0 7 7 7 7 0 0 0 0 0 7 27 0 % E
% Phe: 0 7 0 7 0 7 0 0 0 7 7 0 0 7 0 % F
% Gly: 0 0 7 0 34 14 7 7 34 7 0 27 34 0 27 % G
% His: 0 0 0 0 0 0 0 7 0 0 0 7 0 0 0 % H
% Ile: 0 0 7 7 7 0 0 14 0 7 0 0 7 0 0 % I
% Lys: 0 0 7 7 0 0 0 0 0 14 0 7 14 0 14 % K
% Leu: 0 7 27 14 0 0 7 7 7 7 0 0 0 0 0 % L
% Met: 0 7 0 0 0 7 0 0 0 0 0 14 0 0 0 % M
% Asn: 14 0 14 0 0 14 7 7 7 0 7 0 0 7 0 % N
% Pro: 20 14 14 7 0 7 14 14 14 20 27 14 14 0 0 % P
% Gln: 0 14 14 0 7 0 0 0 7 7 7 0 7 14 14 % Q
% Arg: 14 0 7 7 0 0 0 0 0 27 7 0 14 0 7 % R
% Ser: 34 20 0 7 14 27 14 27 20 7 20 7 7 7 7 % S
% Thr: 0 0 7 0 7 7 7 20 7 0 0 7 0 14 14 % T
% Val: 0 0 0 27 14 7 7 0 7 0 7 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 7 0 0 0 0 0 0 20 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _