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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK6
All Species:
34.55
Human Site:
S560
Identified Species:
54.29
UniProt:
Q9NQU5
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQU5
NP_001122100.1
681
74869
S560
K
D
V
P
K
R
K
S
L
V
G
T
P
Y
W
Chimpanzee
Pan troglodytes
XP_510301
627
67581
F512
V
K
L
S
D
F
G
F
C
A
Q
I
S
K
D
Rhesus Macaque
Macaca mulatta
XP_001093484
681
74821
S560
K
D
V
P
K
R
K
S
L
V
G
T
P
Y
W
Dog
Lupus familis
XP_544614
968
105825
S847
K
D
V
P
K
R
K
S
L
V
G
T
P
Y
W
Cat
Felis silvestris
Mouse
Mus musculus
Q3ULB5
682
74848
S561
K
D
V
P
K
R
K
S
L
V
G
T
P
Y
W
Rat
Rattus norvegicus
Q62829
544
60692
M429
M
V
G
T
P
Y
W
M
A
P
E
V
V
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515215
639
68748
E524
T
P
Y
W
M
A
P
E
V
I
S
R
T
P
Y
Chicken
Gallus gallus
XP_426393
667
74767
S546
K
D
V
P
K
R
K
S
L
V
G
T
P
Y
W
Frog
Xenopus laevis
NP_001082100
650
73749
S533
K
E
V
P
R
R
K
S
L
V
G
T
P
Y
W
Zebra Danio
Brachydanio rerio
XP_001919719
693
77347
S572
K
D
I
P
K
R
K
S
L
V
G
T
P
Y
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
G524
P
K
R
K
S
L
V
G
T
P
Y
W
M
S
P
Honey Bee
Apis mellifera
XP_001122147
624
70155
T509
R
R
K
S
L
V
G
T
P
Y
W
M
S
P
E
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
A457
V
G
T
P
Y
W
M
A
P
E
V
V
T
R
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
T773
E
L
N
L
K
R
T
T
M
V
G
T
P
Y
W
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
T827
E
A
Q
S
K
R
T
T
M
V
G
T
P
Y
W
Conservation
Percent
Protein Identity:
100
52.7
98.5
66.4
N.A.
92.5
30.6
N.A.
62.2
75.9
46.7
52.5
N.A.
44.3
44.9
29.8
N.A.
Protein Similarity:
100
60.7
98.9
67.6
N.A.
95.5
48.4
N.A.
69.9
82.3
61.6
64.5
N.A.
57.5
57.5
47.2
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
0
N.A.
0
100
86.6
93.3
N.A.
0
0
6.6
N.A.
P-Site Similarity:
100
6.6
100
100
N.A.
100
0
N.A.
20
100
100
100
N.A.
0
13.3
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
28
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
41.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
53.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
7
0
7
7
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
40
0
0
7
0
0
0
0
0
0
0
0
0
7
% D
% Glu:
14
7
0
0
0
0
0
7
0
7
7
0
0
0
7
% E
% Phe:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
7
7
0
0
0
14
7
0
0
60
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
0
0
0
0
0
7
0
7
0
0
0
% I
% Lys:
47
14
7
7
54
0
47
0
0
0
0
0
0
7
7
% K
% Leu:
0
7
7
7
7
7
0
0
47
0
0
0
0
0
0
% L
% Met:
7
0
0
0
7
0
7
7
14
0
0
7
7
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
7
7
0
54
7
0
7
0
14
14
0
0
60
14
7
% P
% Gln:
0
0
7
0
0
0
0
0
0
0
7
0
0
0
0
% Q
% Arg:
7
7
7
0
7
60
0
0
0
0
0
7
0
7
7
% R
% Ser:
0
0
0
20
7
0
0
47
0
0
7
0
14
7
0
% S
% Thr:
7
0
7
7
0
0
14
20
7
0
0
60
14
7
0
% T
% Val:
14
7
40
0
0
7
7
0
7
60
7
14
7
0
0
% V
% Trp:
0
0
0
7
0
7
7
0
0
0
7
7
0
0
60
% W
% Tyr:
0
0
7
0
7
7
0
0
0
7
7
0
0
60
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _