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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK6
All Species:
13.64
Human Site:
S409
Identified Species:
21.43
UniProt:
Q9NQU5
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQU5
NP_001122100.1
681
74869
S409
D
P
R
L
L
L
D
S
Y
V
K
I
G
E
G
Chimpanzee
Pan troglodytes
XP_510301
627
67581
A380
Q
G
G
T
Q
T
G
A
L
G
M
G
S
E
Q
Rhesus Macaque
Macaca mulatta
XP_001093484
681
74821
S409
D
P
R
L
L
L
D
S
Y
V
K
I
G
E
G
Dog
Lupus familis
XP_544614
968
105825
S696
D
P
R
M
L
L
D
S
Y
V
K
I
G
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3ULB5
682
74848
S410
D
P
R
L
L
L
D
S
Y
V
K
I
G
E
G
Rat
Rattus norvegicus
Q62829
544
60692
K297
T
G
Q
E
V
A
I
K
Q
M
N
L
Q
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515215
639
68748
R392
V
V
C
L
A
R
E
R
Q
S
G
R
Q
V
A
Chicken
Gallus gallus
XP_426393
667
74767
I409
G
S
T
G
I
V
C
I
A
R
E
K
H
S
G
Frog
Xenopus laevis
NP_001082100
650
73749
A397
S
T
G
I
V
C
I
A
T
I
K
S
S
G
K
Zebra Danio
Brachydanio rerio
XP_001919719
693
77347
N421
D
P
R
S
Y
L
E
N
F
V
K
I
G
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
R392
A
T
D
K
S
T
G
R
Q
V
A
V
K
K
M
Honey Bee
Apis mellifera
XP_001122147
624
70155
Q377
T
E
K
N
T
N
R
Q
V
A
V
K
K
M
D
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
Q325
E
A
E
V
A
I
K
Q
M
N
L
K
D
Q
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
N622
D
P
S
T
K
Y
A
N
L
V
K
I
G
Q
G
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
G676
D
P
R
E
I
Y
R
G
F
T
K
I
G
Q
G
Conservation
Percent
Protein Identity:
100
52.7
98.5
66.4
N.A.
92.5
30.6
N.A.
62.2
75.9
46.7
52.5
N.A.
44.3
44.9
29.8
N.A.
Protein Similarity:
100
60.7
98.9
67.6
N.A.
95.5
48.4
N.A.
69.9
82.3
61.6
64.5
N.A.
57.5
57.5
47.2
N.A.
P-Site Identity:
100
6.6
100
93.3
N.A.
100
0
N.A.
6.6
6.6
6.6
66.6
N.A.
6.6
0
0
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
100
33.3
N.A.
13.3
26.6
33.3
86.6
N.A.
20
6.6
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
28
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
41.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
46.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
14
7
7
14
7
7
7
0
0
0
7
% A
% Cys:
0
0
7
0
0
7
7
0
0
0
0
0
0
0
0
% C
% Asp:
47
0
7
0
0
0
27
0
0
0
0
0
7
0
7
% D
% Glu:
7
7
7
14
0
0
14
0
0
0
7
0
0
40
0
% E
% Phe:
0
0
0
0
0
0
0
0
14
0
0
0
0
0
0
% F
% Gly:
7
14
14
7
0
0
14
7
0
7
7
7
47
7
54
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
0
7
14
7
14
7
0
7
0
47
0
0
0
% I
% Lys:
0
0
7
7
7
0
7
7
0
0
54
20
14
7
7
% K
% Leu:
0
0
0
27
27
34
0
0
14
0
7
7
0
0
0
% L
% Met:
0
0
0
7
0
0
0
0
7
7
7
0
0
7
7
% M
% Asn:
0
0
0
7
0
7
0
14
0
7
7
0
0
0
0
% N
% Pro:
0
47
0
0
0
0
0
0
0
0
0
0
0
0
7
% P
% Gln:
7
0
7
0
7
0
0
14
20
0
0
0
14
27
14
% Q
% Arg:
0
0
40
0
0
7
14
14
0
7
0
7
0
0
0
% R
% Ser:
7
7
7
7
7
0
0
27
0
7
0
7
14
7
0
% S
% Thr:
14
14
7
14
7
14
0
0
7
7
0
0
0
0
0
% T
% Val:
7
7
0
7
14
7
0
0
7
47
7
7
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
14
0
0
27
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _