KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK6
All Species:
10.3
Human Site:
S146
Identified Species:
16.19
UniProt:
Q9NQU5
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQU5
NP_001122100.1
681
74869
S146
D
P
H
G
L
Y
L
S
C
N
G
G
T
P
A
Chimpanzee
Pan troglodytes
XP_510301
627
67581
R125
G
S
P
S
P
K
T
R
E
S
S
L
K
R
R
Rhesus Macaque
Macaca mulatta
XP_001093484
681
74821
S146
D
P
H
G
L
Y
L
S
C
N
G
G
T
P
A
Dog
Lupus familis
XP_544614
968
105825
S433
D
P
H
G
L
Y
L
S
C
N
G
G
T
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3ULB5
682
74848
C147
P
H
G
L
Y
L
S
C
N
G
G
T
P
A
G
Rat
Rattus norvegicus
Q62829
544
60692
K42
L
P
M
A
P
E
E
K
N
K
K
A
R
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515215
639
68748
L137
S
P
R
P
D
G
P
L
G
P
Y
L
S
C
N
Chicken
Gallus gallus
XP_426393
667
74767
G146
G
N
Y
L
N
C
N
G
G
A
K
V
T
R
R
Frog
Xenopus laevis
NP_001082100
650
73749
S141
R
G
S
E
R
N
R
S
E
H
H
R
R
E
R
Zebra Danio
Brachydanio rerio
XP_001919719
693
77347
A146
E
P
H
W
S
E
R
A
R
N
I
H
S
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
H137
I
V
L
P
K
T
S
H
V
A
R
S
N
S
L
Honey Bee
Apis mellifera
XP_001122147
624
70155
R122
P
K
L
R
R
D
Y
R
H
N
N
N
L
P
P
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
P70
E
K
P
V
I
S
R
P
S
N
F
E
H
T
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
R297
G
S
N
S
G
T
L
R
M
K
D
V
F
T
S
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
S295
K
S
E
S
S
S
S
S
N
K
R
H
S
G
D
Conservation
Percent
Protein Identity:
100
52.7
98.5
66.4
N.A.
92.5
30.6
N.A.
62.2
75.9
46.7
52.5
N.A.
44.3
44.9
29.8
N.A.
Protein Similarity:
100
60.7
98.9
67.6
N.A.
95.5
48.4
N.A.
69.9
82.3
61.6
64.5
N.A.
57.5
57.5
47.2
N.A.
P-Site Identity:
100
0
100
100
N.A.
6.6
6.6
N.A.
6.6
6.6
6.6
20
N.A.
0
13.3
6.6
N.A.
P-Site Similarity:
100
6.6
100
100
N.A.
6.6
6.6
N.A.
13.3
13.3
13.3
46.6
N.A.
0
13.3
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
28
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
41.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
7
0
14
0
7
0
14
20
% A
% Cys:
0
0
0
0
0
7
0
7
20
0
0
0
0
7
0
% C
% Asp:
20
0
0
0
7
7
0
0
0
0
7
0
0
0
7
% D
% Glu:
14
0
7
7
0
14
7
0
14
0
0
7
0
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% F
% Gly:
20
7
7
20
7
7
0
7
14
7
27
20
0
7
7
% G
% His:
0
7
27
0
0
0
0
7
7
7
7
14
7
0
0
% H
% Ile:
7
0
0
0
7
0
0
0
0
0
7
0
0
0
7
% I
% Lys:
7
14
0
0
7
7
0
7
0
20
14
0
7
0
0
% K
% Leu:
7
0
14
14
20
7
27
7
0
0
0
14
7
7
7
% L
% Met:
0
0
7
0
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
7
7
0
7
7
7
0
20
40
7
7
7
0
7
% N
% Pro:
14
40
14
14
14
0
7
7
0
7
0
0
7
27
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
0
7
7
14
0
20
20
7
0
14
7
14
14
27
% R
% Ser:
7
20
7
20
14
14
20
34
7
7
7
7
20
7
14
% S
% Thr:
0
0
0
0
0
14
7
0
0
0
0
7
27
14
0
% T
% Val:
0
7
0
7
0
0
0
0
7
0
0
14
0
0
0
% V
% Trp:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
7
20
7
0
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _