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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TIGAR
All Species:
10.61
Human Site:
S157
Identified Species:
23.33
UniProt:
Q9NQ88
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQ88
NP_065108.1
270
30063
S157
K
E
Q
F
S
Q
G
S
P
S
N
C
L
E
T
Chimpanzee
Pan troglodytes
XP_522324
270
30026
S157
K
E
Q
F
S
Q
G
S
P
S
N
C
L
E
T
Rhesus Macaque
Macaca mulatta
XP_001118082
270
29997
S157
K
E
Q
F
S
Q
G
S
P
G
N
C
L
E
T
Dog
Lupus familis
XP_543863
316
34501
A203
N
E
Q
C
S
Q
G
A
P
S
N
S
L
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZA9
269
29172
A157
R
E
S
V
L
P
G
A
P
G
S
G
L
E
S
Rat
Rattus norvegicus
NP_001020235
178
19233
A67
R
E
N
F
L
P
G
A
P
D
N
C
L
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518492
261
26811
R148
Q
L
V
L
A
D
T
R
Q
K
T
E
G
P
T
Chicken
Gallus gallus
XP_417232
280
30888
S161
H
G
A
A
S
R
S
S
G
T
C
E
E
E
S
Frog
Xenopus laevis
Q4V7R0
275
30639
A157
K
E
K
S
E
L
G
A
S
G
M
V
G
I
M
Zebra Danio
Brachydanio rerio
Q29RA5
256
28162
N145
A
M
Y
Q
R
I
A
N
D
H
Q
D
K
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784615
238
26671
R127
G
E
S
F
Q
V
A
R
Q
R
V
V
K
A
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
95.5
72.4
N.A.
72.2
43.7
N.A.
37.7
56
51.6
40.3
N.A.
N.A.
N.A.
N.A.
31.1
Protein Similarity:
100
99.2
98.1
77.8
N.A.
84.8
54.4
N.A.
51.4
72.8
68.3
58.1
N.A.
N.A.
N.A.
N.A.
50
P-Site Identity:
100
100
93.3
73.3
N.A.
33.3
53.3
N.A.
6.6
20
20
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
93.3
80
N.A.
60
73.3
N.A.
20
40
33.3
6.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
10
10
0
19
37
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
10
37
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
10
10
0
10
0
0
0
% D
% Glu:
0
73
0
0
10
0
0
0
0
0
0
19
10
64
0
% E
% Phe:
0
0
0
46
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
10
10
0
0
0
0
64
0
10
28
0
10
19
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% I
% Lys:
37
0
10
0
0
0
0
0
0
10
0
0
19
0
0
% K
% Leu:
0
10
0
10
19
10
0
0
0
0
0
0
55
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
10
% M
% Asn:
10
0
10
0
0
0
0
10
0
0
46
0
0
0
0
% N
% Pro:
0
0
0
0
0
19
0
0
55
0
0
0
0
10
0
% P
% Gln:
10
0
37
10
10
37
0
0
19
0
10
0
0
0
10
% Q
% Arg:
19
0
0
0
10
10
0
19
0
10
0
0
0
0
0
% R
% Ser:
0
0
19
10
46
0
10
37
10
28
10
10
0
0
28
% S
% Thr:
0
0
0
0
0
0
10
0
0
10
10
0
0
0
46
% T
% Val:
0
0
10
10
0
10
0
0
0
0
10
19
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _