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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAN
All Species:
31.82
Human Site:
S228
Identified Species:
50
UniProt:
Q9NQ55
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQ55
NP_001035754.1
473
53194
S228
M
S
R
L
Q
D
I
S
E
L
L
A
T
G
A
Chimpanzee
Pan troglodytes
XP_001150990
706
78742
S228
M
S
R
L
Q
D
I
S
E
L
L
A
T
G
A
Rhesus Macaque
Macaca mulatta
XP_001100297
471
52923
S228
M
S
R
L
Q
D
I
S
E
L
L
A
T
G
A
Dog
Lupus familis
XP_533920
792
88144
S228
M
S
R
L
Q
D
I
S
E
L
L
A
T
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q91YU8
470
52707
S228
M
S
R
L
Q
D
I
S
E
L
L
A
T
G
V
Rat
Rattus norvegicus
NP_001011980
470
52521
S228
M
S
R
L
Q
D
I
S
E
L
L
A
S
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519003
490
55177
S228
M
R
R
L
Q
D
I
S
E
L
L
V
T
G
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_958871
522
59529
S227
M
S
K
L
E
D
I
S
E
L
L
M
K
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VDE5
460
53074
V227
L
G
K
C
N
E
V
V
D
F
V
T
K
D
G
Honey Bee
Apis mellifera
XP_395421
413
48031
S221
C
L
N
Y
N
A
T
S
K
T
I
D
L
R
H
Nematode Worm
Caenorhab. elegans
NP_491108
573
63766
S256
G
K
N
I
P
N
L
S
T
Y
K
D
I
S
D
Sea Urchin
Strong. purpuratus
XP_787585
300
34175
H111
P
T
L
T
F
K
V
H
K
Y
T
L
A
K
D
Poplar Tree
Populus trichocarpa
XP_002302711
297
33281
E108
T
L
T
F
K
I
H
E
Y
S
L
A
A
D
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ASU7
345
38823
L156
S
G
F
G
S
Q
E
L
H
L
K
L
A
T
I
Baker's Yeast
Sacchar. cerevisiae
P38789
453
51746
H237
S
K
T
V
P
N
L
H
R
K
E
D
I
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.1
95.7
48.8
N.A.
73.3
73.5
N.A.
62
N.A.
N.A.
53
N.A.
35
38.9
31.4
36.3
Protein Similarity:
100
65.4
97.4
54
N.A.
81.6
81.8
N.A.
75.3
N.A.
N.A.
70.1
N.A.
57.5
59.2
49.5
47.9
P-Site Identity:
100
100
100
100
N.A.
93.3
86.6
N.A.
86.6
N.A.
N.A.
66.6
N.A.
0
6.6
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
N.A.
N.A.
80
N.A.
40
20
26.6
20
Percent
Protein Identity:
28.7
N.A.
N.A.
32.9
25.5
N.A.
Protein Similarity:
42.9
N.A.
N.A.
50.5
44.8
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
20
N.A.
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
0
0
0
0
47
20
0
34
% A
% Cys:
7
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
54
0
0
7
0
0
20
0
14
14
% D
% Glu:
0
0
0
0
7
7
7
7
54
0
7
0
0
0
0
% E
% Phe:
0
0
7
7
7
0
0
0
0
7
0
0
0
0
0
% F
% Gly:
7
14
0
7
0
0
0
0
0
0
0
0
0
54
7
% G
% His:
0
0
0
0
0
0
7
14
7
0
0
0
0
0
7
% H
% Ile:
0
0
0
7
0
7
54
0
0
0
7
0
14
0
7
% I
% Lys:
0
14
14
0
7
7
0
0
14
7
14
0
14
7
0
% K
% Leu:
7
14
7
54
0
0
14
7
0
60
60
14
7
0
0
% L
% Met:
54
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
14
0
14
14
0
0
0
0
0
0
0
0
0
% N
% Pro:
7
0
0
0
14
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
47
7
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
7
47
0
0
0
0
0
7
0
0
0
0
7
0
% R
% Ser:
14
47
0
0
7
0
0
67
0
7
0
0
7
14
7
% S
% Thr:
7
7
14
7
0
0
7
0
7
7
7
7
40
7
0
% T
% Val:
0
0
0
7
0
0
14
7
0
0
7
7
0
0
27
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
7
14
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _