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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCUBE2
All Species:
18.18
Human Site:
S227
Identified Species:
50
UniProt:
Q9NQ36
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQ36
NP_066025.1
999
109957
S227
G
N
G
G
C
Q
H
S
C
D
D
T
A
D
G
Chimpanzee
Pan troglodytes
XP_001169046
997
109805
S224
G
N
G
G
C
Q
H
S
C
D
D
T
A
D
G
Rhesus Macaque
Macaca mulatta
XP_001096605
965
106637
S193
G
N
G
G
C
Q
H
S
C
E
D
T
A
D
G
Dog
Lupus familis
XP_542500
1000
110245
S229
G
N
G
G
C
Q
H
S
C
E
D
T
A
D
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJS0
997
109905
S225
G
N
G
G
C
Q
H
S
C
E
D
T
A
E
G
Rat
Rattus norvegicus
O88281
1574
165428
I261
G
N
G
G
C
M
H
I
C
Q
E
L
R
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510365
931
103588
K159
G
N
G
G
C
Q
H
K
C
D
D
T
V
N
G
Chicken
Gallus gallus
O73775
704
78120
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5G872
1010
112158
I210
G
N
G
G
C
Q
H
I
C
E
D
T
E
Q
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
93.4
91.6
N.A.
89.1
22.2
N.A.
74.9
20.8
N.A.
67.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99
94.9
93.8
N.A.
93.8
31.9
N.A.
82.9
34.3
N.A.
78.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
46.6
N.A.
80
0
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
53.3
N.A.
86.6
0
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
56
0
0
% A
% Cys:
0
0
0
0
89
0
0
0
89
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
34
78
0
0
45
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
45
12
0
12
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
89
0
89
89
0
0
0
0
0
0
0
0
0
12
78
% G
% His:
0
0
0
0
0
0
89
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
23
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
12
% L
% Met:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
89
0
0
0
0
0
0
0
0
0
0
0
12
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
78
0
0
0
12
0
0
0
12
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% R
% Ser:
0
0
0
0
0
0
0
56
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
78
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _