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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RIC8A
All Species:
38.48
Human Site:
T381
Identified Species:
76.97
UniProt:
Q9NPQ8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NPQ8
NP_068751.4
530
59612
T381
N
K
L
V
R
L
M
T
H
L
D
T
D
V
K
Chimpanzee
Pan troglodytes
XP_001143336
530
59630
T381
N
K
L
V
R
L
M
T
H
L
D
T
D
V
K
Rhesus Macaque
Macaca mulatta
XP_001083920
528
59373
T379
N
K
L
V
R
L
M
T
H
L
D
T
D
V
K
Dog
Lupus familis
XP_848262
529
59468
T380
N
K
L
V
R
L
M
T
H
L
D
T
D
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q3TIR3
530
59828
T381
N
K
L
V
R
L
M
T
H
L
D
T
D
V
K
Rat
Rattus norvegicus
Q80ZG1
529
59815
T381
N
K
L
V
R
L
M
T
H
L
D
T
D
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508465
507
56644
K366
F
M
E
K
R
I
D
K
G
S
C
Y
R
E
G
Chicken
Gallus gallus
Q5ZL77
539
61485
T390
N
K
L
V
R
L
M
T
H
I
D
T
D
V
K
Frog
Xenopus laevis
Q45TX8
539
61255
T390
N
K
L
V
R
L
M
T
H
V
D
T
D
V
K
Zebra Danio
Brachydanio rerio
Q642H7
548
61977
T394
N
K
L
V
R
L
M
T
H
I
D
T
D
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W358
573
65583
T422
N
H
L
C
R
F
L
T
L
P
A
M
I
L
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9GSX9
566
63429
M413
R
G
R
I
A
R
I
M
M
L
P
S
S
T
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
93
89.4
N.A.
88.1
86.5
N.A.
42.8
67.7
58.6
57.8
N.A.
31.9
N.A.
26.5
N.A.
Protein Similarity:
100
99.4
94.9
94.1
N.A.
93.7
92.2
N.A.
59.6
80.5
74.9
73.5
N.A.
50.6
N.A.
46.6
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
93.3
93.3
93.3
N.A.
26.6
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
100
100
100
N.A.
46.6
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
0
0
75
0
75
0
0
% D
% Glu:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% E
% Phe:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
9
% G
% His:
0
9
0
0
0
0
0
0
75
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
9
9
0
0
17
0
0
9
0
0
% I
% Lys:
0
75
0
9
0
0
0
9
0
0
0
0
0
0
84
% K
% Leu:
0
0
84
0
0
75
9
0
9
59
0
0
0
9
0
% L
% Met:
0
9
0
0
0
0
75
9
9
0
0
9
0
0
0
% M
% Asn:
84
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
9
0
92
9
0
0
0
0
0
0
9
0
9
% R
% Ser:
0
0
0
0
0
0
0
0
0
9
0
9
9
0
0
% S
% Thr:
0
0
0
0
0
0
0
84
0
0
0
75
0
9
0
% T
% Val:
0
0
0
75
0
0
0
0
0
9
0
0
0
75
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _