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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZDHHC4
All Species:
30
Human Site:
Y230
Identified Species:
47.14
UniProt:
Q9NPG8
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NPG8
NP_001127859.1
344
39787
Y230
S
D
L
Y
Q
E
T
Y
I
D
D
L
G
H
L
Chimpanzee
Pan troglodytes
XP_001142662
344
39946
Y230
S
D
L
Y
Q
E
T
Y
I
D
D
L
G
H
L
Rhesus Macaque
Macaca mulatta
XP_001091630
344
39843
Y230
S
D
L
Y
Q
E
T
Y
V
D
D
L
G
H
L
Dog
Lupus familis
XP_536886
343
39778
Y230
S
D
L
Y
L
E
T
Y
I
D
H
L
G
H
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9D6H5
343
39509
Y230
S
D
L
Y
Q
E
T
Y
L
D
D
V
G
H
F
Rat
Rattus norvegicus
Q5FVR1
343
39379
Y230
S
N
L
Y
Q
E
T
Y
L
D
D
L
G
R
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506292
476
54090
Y364
S
N
M
T
L
G
S
Y
I
D
D
E
G
Q
E
Chicken
Gallus gallus
XP_414861
343
39066
Y232
S
N
M
M
H
G
S
Y
I
D
D
Q
G
Q
E
Frog
Xenopus laevis
NP_001086024
326
37591
L219
A
F
L
L
K
V
V
L
L
S
H
M
M
S
A
Zebra Danio
Brachydanio rerio
NP_956343
345
39869
Y232
T
G
L
L
H
A
H
Y
I
D
E
Q
G
I
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q8I0G4
403
46434
I292
K
D
A
F
N
H
G
I
R
A
N
Y
R
E
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002328533
299
33861
T199
N
C
I
G
E
R
N
T
R
Y
F
L
A
F
L
Maize
Zea mays
NP_001150688
392
44335
V242
K
I
I
Y
I
L
T
V
Y
Y
G
I
D
N
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q3EBC2
397
44927
V242
R
V
V
H
I
L
T
V
Y
Y
G
V
D
K
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RWM9
429
49597
Q244
M
P
W
W
T
S
T
Q
A
W
N
S
G
D
L
Conservation
Percent
Protein Identity:
100
98.2
94.1
77
N.A.
73.8
70.9
N.A.
45.1
50
45.6
45.5
N.A.
N.A.
N.A.
23
N.A.
Protein Similarity:
100
98.8
96.5
86.6
N.A.
85.1
83.1
N.A.
54.4
66.2
63.9
61.7
N.A.
N.A.
N.A.
35.9
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
80
73.3
N.A.
40
40
6.6
33.3
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
80
N.A.
93.3
86.6
N.A.
60
60
33.3
46.6
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
25.2
25.2
N.A.
23.9
N.A.
22.1
Protein Similarity:
39.8
42.6
N.A.
41.5
N.A.
38.4
P-Site Identity:
13.3
13.3
N.A.
6.6
N.A.
20
P-Site Similarity:
33.3
33.3
N.A.
26.6
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
0
7
0
0
7
7
0
0
7
0
7
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
40
0
0
0
0
0
0
0
60
47
0
14
7
0
% D
% Glu:
0
0
0
0
7
40
0
0
0
0
7
7
0
7
14
% E
% Phe:
0
7
0
7
0
0
0
0
0
0
7
0
0
7
20
% F
% Gly:
0
7
0
7
0
14
7
0
0
0
14
0
67
0
0
% G
% His:
0
0
0
7
14
7
7
0
0
0
14
0
0
34
0
% H
% Ile:
0
7
14
0
14
0
0
7
40
0
0
7
0
7
7
% I
% Lys:
14
0
0
0
7
0
0
0
0
0
0
0
0
7
0
% K
% Leu:
0
0
54
14
14
14
0
7
20
0
0
40
0
0
34
% L
% Met:
7
0
14
7
0
0
0
0
0
0
0
7
7
0
0
% M
% Asn:
7
20
0
0
7
0
7
0
0
0
14
0
0
7
0
% N
% Pro:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
34
0
0
7
0
0
0
14
0
14
7
% Q
% Arg:
7
0
0
0
0
7
0
0
14
0
0
0
7
7
0
% R
% Ser:
54
0
0
0
0
7
14
0
0
7
0
7
0
7
14
% S
% Thr:
7
0
0
7
7
0
60
7
0
0
0
0
0
0
0
% T
% Val:
0
7
7
0
0
7
7
14
7
0
0
14
0
0
0
% V
% Trp:
0
0
7
7
0
0
0
0
0
7
0
0
0
0
0
% W
% Tyr:
0
0
0
47
0
0
0
60
14
20
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _