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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DMAP1 All Species: 32.73
Human Site: S458 Identified Species: 48
UniProt: Q9NPF5 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NPF5 NP_001029195.1 467 52993 S458 R R E S A S S S S S V K K A K
Chimpanzee Pan troglodytes XP_513103 672 74885 S663 R R E S A S S S S S V K K A K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532609 501 56456 S491 K R R E S A S S S S S V K K A
Cat Felis silvestris
Mouse Mus musculus Q9JI44 468 53111 S459 R R E S A S S S S S V K K A K
Rat Rattus norvegicus NP_001015006 468 53155 S458 K R R E S A S S S S S V K K A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422417 512 58586 Q502 R K V V G A E Q G A L R S P T
Frog Xenopus laevis NP_001087876 464 53153 S455 R R E S A S S S S S V K K M K
Zebra Danio Brachydanio rerio NP_956549 464 53441 S455 R R E S A S S S S S I K K V K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611503 433 50230 T425 P S L V P I K T E A L D N S T
Honey Bee Apis mellifera XP_392117 440 50974 S432 D I I D V V G S P S M P S I T
Nematode Worm Caenorhab. elegans NP_740945 486 55822 S471 S F V S S S N S P S T S A A S
Sea Urchin Strong. purpuratus XP_001197869 455 52143 G447 R L A A V E Q G N V L K K L K
Poplar Tree Populus trichocarpa XP_002320280 443 49457 H432 E N P S S P A H K R P R K L K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_850470 441 49805 S427 G R Q A D T P S P A H K R P R
Baker's Yeast Sacchar. cerevisiae P53201 476 55194 I455 Q E E L L K K I N T L I D L K
Red Bread Mold Neurospora crassa Q870Q1 733 80376 S721 K R S A S V L S N A S D K S T
Conservation
Percent
Protein Identity: 100 69.4 N.A. 92.8 N.A. 97.8 98.2 N.A. N.A. 76.5 83 79.8 N.A. 47.1 53.7 38 51.8
Protein Similarity: 100 69.4 N.A. 92.8 N.A. 98 98.7 N.A. N.A. 81 89.9 86.9 N.A. 67 68.3 55.9 64.8
P-Site Identity: 100 100 N.A. 40 N.A. 100 40 N.A. N.A. 6.6 93.3 86.6 N.A. 0 13.3 33.3 26.6
P-Site Similarity: 100 100 N.A. 60 N.A. 100 60 N.A. N.A. 40 93.3 93.3 N.A. 26.6 20 46.6 46.6
Percent
Protein Identity: 30.1 N.A. N.A. 26.9 21.4 22.2
Protein Similarity: 46.2 N.A. N.A. 44.7 41.3 34.9
P-Site Identity: 20 N.A. N.A. 20 13.3 20
P-Site Similarity: 40 N.A. N.A. 60 40 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 19 32 19 7 0 0 25 0 0 7 25 13 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 7 7 0 0 0 0 0 0 13 7 0 0 % D
% Glu: 7 7 38 13 0 7 7 0 7 0 0 0 0 0 0 % E
% Phe: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 0 0 0 7 0 7 7 7 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 7 0 0 7 0 0 0 0 % H
% Ile: 0 7 7 0 0 7 0 7 0 0 7 7 0 7 0 % I
% Lys: 19 7 0 0 0 7 13 0 7 0 0 44 63 13 50 % K
% Leu: 0 7 7 7 7 0 7 0 0 0 25 0 0 19 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 7 0 0 7 0 % M
% Asn: 0 7 0 0 0 0 7 0 19 0 0 0 7 0 0 % N
% Pro: 7 0 7 0 7 7 7 0 19 0 7 7 0 13 0 % P
% Gln: 7 0 7 0 0 0 7 7 0 0 0 0 0 0 0 % Q
% Arg: 44 57 13 0 0 0 0 0 0 7 0 13 7 0 7 % R
% Ser: 7 7 7 44 32 38 44 69 44 57 19 7 13 13 7 % S
% Thr: 0 0 0 0 0 7 0 7 0 7 7 0 0 0 25 % T
% Val: 0 0 13 13 13 13 0 0 0 7 25 13 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _